Found 16 Neurosurgery trials
A listing of Neurosurgery medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
ImmuneSense Study- Safety and Efficacy of IGV-001 an Autologus Cell Immunotherapy With Antisense Oligonucleotide (IMV-001) Targeting IGF-1R in Newly Diagnosed Patients With Glioblastoma Multiforme
Phase 2
The purpose of this study is to see how safe the study medicine, IGV-001 plus standard of care (SOC), is and to compare IGV-001 with placebo (only standard of care) to see if it works in slowing GBM tumor regrowth. Participants for this study will be recruited from the patient …
A Clinical Trial to Evaluate the Safety and Efficacy of Staged Bilateral Exablate Treatment of Medication Refractory Essential Tremor
The Exablate Model 4000 Type-1.0/1.1 Neuro system involves using an advanced, non-invasive technique currently approved by the Food and Drug Administration (FDA) to treat one side of your brain in a procedure called a thalamotomy (lesion the thalamus). This procedure involves performing an ablation (lesion) of an area of the …
WEB PAS
The primary objective of this post-market surveillance study is to evaluate the long-term safety and effectiveness of the WEB® Device within currently approved indications for use. Key effectiveness outcome is the proportion of subjects with adequate aneurysm occlusion at one year after treatment. Key safety outcome includes the proportion of …
DBS Electrophysiological Recordings
The objective of this study is to obtain neural recordings from deep brain structures while performing simple intraoperative tasks in order to improve the understanding of temporal relationship of deep neural signals and the performance of simple psychomotor, cognitive, and/or executive tasks. The standard DBS surgery provides an opportunity to …
MT-3921- Phase 2 Study to Assess the Efficacy and Safety of MT-3921 in Subjects with Acute Traumatic Cervical Spinal Cord Injury
Phase 2
MT-3921 is an investigational monoclonal antibody therapy for patients with severe (AIS grade A-C) traumatic cervical spinal cord injury (SCIs). This study aims to compare the efficacy of MT-3921 to a placebo with regard to improving patients sensory and motor function and overall quality of life. Additionally this study aims …
Circulating Biomarkers for Glioma
Subjects will be recruited from the Radiation Oncology and Neurosurgery practices at the Hospital of the University of Pennsylvania. The treating radiation oncologist will determine if the patient is a potential research candidate and has the capacity to consent. The goal of this study is to collect and analyze blood …
Improving Clinical Outcomes of Auditory Brainstem Implantation with Speech-Evoked Auditory Brainstem Responses
The goal of this study is to improve the reliability of acquiring open-set speech recognition following ABI placement for retrocochlear deafness, to evaluate whether state of consciousness influences speech-based ABR. The researchers hypothesize that: 1) It will be possible to elicit speech-based ABR from surgically anesthetized patients. 2) Surgically anesthetized …
Responsive Neurostimulation for Loss of Control Over Eating
This is an early feasibility study looking at the safety, feasibility, and potential benefit of a medical device, called the NeuroPace RNS System, for people suffering from obesity, with uncontrolled eating habits.
FRED-X
Please refer to Section 6.1 of the attached protocol. Please refer to Section 6.5 of the attached protocol. Please refer to Section 6.5 of the attached protocol.
PD DBS Sleep Study
The purpose of this study is to gain a better understanding of how signals in the brain contribute to abnormal sleep behavior in patients with Parkinson's Disease (PD).
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