Penn Medicine is conducting medical studies to develop new diagnostic and clinical treatments to improve current standards of care.
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Recently Added/Updated Trials
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T-Cell Response to Vaccination
The purpose of this study is to see how your body responds to a vaccine and how your body forms a protective response after vaccination ...Read more -
Harnessing Hormonal Variation to Probe Neural Mechanisms of OCD and Symptom Reduction by EX/RP
Studies show that hormones affect the brain’s fear extinction network, which is relevant for therapy involving exposure and ritual prevention (EX/RP), a first ... Read more -
Rehabilitation Using Community-Based Affordable Robotic Exercise Systems (Rehab CARES): Usability Study
Stroke is the leading cause of serious long-term disability. It is estimated that 5.86.5 million people currently live with stroke related disability in ...Read more -
Towards Objective Metrics to Quantify the Role of HIV and Increasing Cognitive Demand on Instrumental ADLs in People Aging with HIV
Read moreThe objective of this proposal is to examine the utility of a robot-based approach to study instrumental activities of daily living (IADLs) function and cognitive-motor ... -
Study for the Long-term Safety and Efficacy in Participants with Advanced Tumors Who Are Currently on Treatment or in Follow-up in a Pembrolizumab Trial.
The purpose of this study is to continue to collect long term information on the safety of pembrolizumab or pembrolizumab-based combinations that you received or ... Read more
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A Study to Evaluate the Safety of Trabectedin Ewing Sarcoma Patients in Combination with Low Dose Irinotecan and 3'-Deoxy-3'-18F Fluorothymidine (18F-FLT) Imaging
This study evaluates the trabectedin and irinotecan in the treatment of Ewings sarcoma, with a EWS-FLI1 mutation. Patients will also receive an infusion of 18F-FLT ... Read more
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A Umbrella Study with Rolling Arms of Investigational Agents with Pembrolizumab in Combination with Chemotherapy in Treatment-Naive Patients with Advanced Non-small Cell Lung Cancer (NSCLC)
This is a substudy of an umbrella study (MK-3475-U1). Subjects will be enrolled to the screening protocol and then subsequently enrolled to one of the ... Read more
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A Study with Rolling Arms of Investigational Agents in Combination with Pembrolizumab in Patients with Advanced Non-small Cell Lung Cancer (NSCLC)
This is a substudy of an umbrella study (MK-3475-U1). Subjects will be enrolled to the screening protocol and then subsequently enrolled to one of the ... Read more