Found 5 Down's Syndrome trials
A listing of Down's Syndrome medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
Bial GBA
I am requesting a reliance agreement with an external IRB The purpose is to investigate the effects, safety, and tolerability of BIA 28-6156. This study is also meant to find out if the effects, safety, and tolerability vary in people with different forms of the GBA1 gene. The ffects will …
A Study to Evaluate the Effectiveness and Safety of CAEL-101 in Patients With Mayo Stage IIIb AL Amyloidosis
Phase 3
AL (or light chain) amyloidosis begins in the bone marrow where abnormal proteins misfold and create free light chains that cannot be broken down. These free light chains bind together to form amyloid fibrils that build up in the extracellular space of organs, affecting the kidneys, heart, liver, spleen, nervous …
A Trial of Robotic Versus Open Hysterectomy Surgery in Cervix Cancer (ROCC)
The purpose of this study is to investigate if minimally invasive surgery, called robotic assisted laparoscopy (small incision surgery), is better or worse than open surgery (otherwise known as a laparotomy) when performing a radical hysterectomy for cervical cancer. A radical hysterectomy is surgery to remove the uterus, cervix, the …
A Randomized Trial Evaluating the Efficacy and Safety of Control-IQ Technology in Adults with Type 2 Diabetes Using Basal-Bolus Insulin Therapy (2IQP)
If you have type 2 diabetes and use short and long acting insulin then we would love to talk to you! The study is being done to learn if an automated insulin delivery (AID) system can safely control blood sugar in people with type 2 diabetes. We will refer …
Cardiometabolic Effects of Dipeptidyl Peptidase IV and Related Pathways
DPP4 is an enzyme that breaks down proteins that may affect blood sugar and the heart. We will recruit individuals from the Penn Biobank (cases, controls). Participants will be asked to complete a meal test, DXA, and echocardiogram with exercise. A cardiac MRI and related pilot study are optional.
