Cognitive Impact of Learned Non-use Behavior in Stroke Patients

Brief description of study

The purpose of this study is to investigate the cause of brain’s reduced control of muscles in the arm after stroke. We will use brain sensors (EEG) and muscle sensors (EMG) to understand the transfer of information from the brain to the muscles in the arm. We will also study the readiness potential which is a signal that indicates that the brain is preparing for a movement before the movement actually begins.

Detailed description of study

The study activities will take place at Penn Medicine Rittenhouse at 1800 Lombard Street, Philadelphia, PA 19146.

We are looking for two types of individuals.

Participants for our control group: Healthy people without stroke and without brain impairments who are above the age of 18.
Participants for our Test group: People living with stroke who are above the age of 18.

The study should only take one or two sessions of approximately three hours with rest times built in and involves you completing cognitive and motor clinical assessment scales and then recording brain and muscle activities with an EEG cap and EMG sensors while completing a reach and grasp task.

The study pays $50.00 compensation at the end of the session. We are doing this study to understand two things:

to find out why some stroke survivors don't use their affected arm
we also want to see how thinking and memory (cognition) affect people who had a stroke and don't use their hurt arm much.

Eligibility of study

You may be eligible for this study if you meet the following criteria:

Conditions:
Stroke,Brain
Age: Between 18 Years - 100 Years
Gender: All

Inclusion

Must be, over 18 years old medically stable able
Able to give informed consent willing toprovide demographic, medical, and rehabilitation historical data
If stroke – has motor impai rment in arm and is able to reach out at elbow and open and close hand
If healthy volunteer --- no neurological dysfunction no upper limb motor dysfunction due to any kind of osteoarticular or peripheral neuromuscular disease

Exclusion

Have a history of traumatic brain injury, drug and/or alcohol abuse.
Taking medication that would impair cognitive ability.
Has had multiple strokes affecting upper arm.
Unable to give consent.

Updated on 17 Apr 2024. Study ID: 854660

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