Yellow fever vaccination
Brief description of study
The purpose of this study is to investigate the immune response in LNs and blood of healthy individuals vaccinated against yellow fever. Samples will be collected by ultrasound-guided fine needle aspiration (FNA) of axillary LNs, and we will also collect blood samples by phlebotomy. Vaccination is not administered as part of the protocol, but the vaccine status of participants will be included in downstream analysis. From the cohort of vaccinated donors, we will take samples within 14 +/- 2 days post-vaccination, and/or within 2 +/- 1 months post-vaccination, and/or within 6 +/- 2 months post-vaccination. Samples will be analyzed using methods such as flow cytometry and single-cell sequencing to determine cellular and transcriptomic responses to YFV. Not applicable. This study involves the procurement of lymph node samples through ultrasound-guided fine needle aspiration and blood samples. Not applicable. This study involves the procurement of lymph node samples through ultrasound-guided fine needle aspiration and blood samples.
Eligibility of study
You may be eligible for this study if you meet the following criteria:
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Conditions:
Medical Research
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Age: - 99 Years
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Gender: All
TBD
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