NAC Attack: Phase III Multicenter Randomized Parallel Double Masked Placebo-Controlled Study Evaluating the Efficacy and Safety of Oral N-Acetylcysteine in Patients with Retinitis Pigmentosa

NAC Attack: Phase III  Multicenter  Randomized  Parallel  Double Masked  Placebo-Controlled Study Evaluating the Efficacy and Safety of Oral N-Acetylcysteine in Patients with Retinitis Pigmentosa

Brief description of study

Currently, this study is recruiting among patients at Penn Medicine. It is not accepting non-Penn Medicine patient participants.

The objective of the study will be to evaluate the efficacy and safety of oral N-acetylcysteine (NAC) in patients with retinitis pigmentosa (RP). The study is a multi-center, randomized, placebo-controlled study where adult patients diagnosed with RP will be asked to take 1800mg NAC bid or a placebo. Patients will be followed for 45 months with a series of clinic visits, tele-visits and phone calls, and safety and efficacy will be assessed using tests to measure visual function and structure.

Eligibility of study

You may be eligible for this study if you meet the following criteria:

  • Conditions:
    retinitis pigmentosa
  • Age: Between 18 Years - 99 Years
  • Gender: All


Updated on 09 Mar 2024. Study ID: 853552
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Interested in the study

Select a study center that’s convenient for you, and get in touch with the study team.

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