Research Study on Whether a Combination of 2 Medicines Works in People With Non-alcoholic Steatohepatitis (NASH)

Brief description of study

This study is being done to see if a combination of 2 medicines (called NNC0194-0499 and semaglutide) can reduce liver damage in patients with non alcoholic steatohepatitis (NASH). NNC0194-0499 is a new medicine which works in the liver. Semaglutide is a well-known medicine, which is already used by doctors to treat type 2 diabetes in many countries. It also helps with weight loss and may reduce liver damage, and so prevent future liver complications. It works in a different way to NNC0194 0499. The 2 medicines may work better together than on their own. The study will also look at a combination of semaglutide and another weight-loss medicine called NNC0174-0833, which may be another treatment option for NASH.

Eligibility of study

You may be eligible for this study if you meet the following criteria:

Conditions:
Non-alcoholic Steatohepatitis,NASH
Age: Between 18 Years - 99 Years
Gender: All

Male or Female Age 18 or older Histological evidence of NASH

Updated on 09 Mar 2024. Study ID: 849168

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