PPS Study- Screening and Classification of Pentosan-Associated Maculopathy in Patients with Interstitial Cystitis

Brief description of study

The primary objective of this study is to determine the prevalence of retinal changes in patients using pentosan polysulfate sodium (PPS) for treatment of interstitial cystitis and further characterize this condition using multimodal imaging. Additionally, this study aims to identify additional clinical findings associated with PPS maculopathy and to gain insight into the pathophysiology of PPS maculopathy based on findings from multimodal imaging.

The primary endpoint of the study will be to identify the prevalence of PPS-associated maculopathy in patients receiving PPS for interstitial cystitis. The secondary endpoint will be to identify potential factors (e.g. cumulative dose exposure) associated with elevated risk of developing PPS-associated maculopathy.

Eligibility of study

You may be eligible for this study if you meet the following criteria:

Conditions:
interstitial cystitis,retina
Age: Between 18 Years - 99 Years
Gender: All

History of interstitial cystitis
Currently or previously prescribed pentosan polysulfate sodium
Exclusion includes: Significant media opacities which may interfere with fundus imaging.

Updated on 09 Mar 2024. Study ID: 848624

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