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Found 193 medicine trials

A listing of medicine medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

 Research Study on Whether Semaglutide Works in People With Non-alcoholic Steatohepatitis (NASH)

Research Study on Whether Semaglutide Works in People With Non-alcoholic Steatohepatitis (NASH)

18-99 years
All genders
Phase 3
Semaglutide is a medicine studied in patients with NASH. Semaglutide is a well-known medicine, which is already used by doctors to treat type 2 diabetes in many countries. Participants will need to inject themselves with medicine under the skin. Participants will need to do this once a week. The study …
 LCAT Deficiency Disorders: natural history and identification of biomarkers

LCAT Deficiency Disorders: natural history and identification of biomarkers

1-99 years
All genders
Familial lecithin:cholesterol acyl transferase (LCAT) deficiency (FLD) is a rare, hereditary disease with no treatment. It is caused by mutations in the gene for LCAT, an enzyme that is made in the liver and plays a role in the body’s ability to process (“metabolize”) cholesterol. People with FLD have very …
 RevitaT2Di Pivotal Study (REVITALIZE 1)

RevitaT2Di Pivotal Study (REVITALIZE 1)

21-70 years
All genders
The Revitalize-1 Study will look at a potential procedure called duodenal mucosal resurfacing (DMR). The DMR procedure acts on the first layer (mucosa) of the duodenum (the part of the small intestine located immediately after the stomach). By removing an excess layer, the treatment may improve blood sugar control. This …

Pilot, Single Center, Feasibility Study of Cuirass Biphasic Ventilator in Chronic Obstructive Pulmonary Disease Patients

21-79 years
All genders
Phase 1
The research study is being conducted to learn about the work of breathing support that an external breathing support device can provide compared to a person’s baseline ability. The research study is sponsored by RightAir Inc, the makers of the device being investigated, the AIR-AD cuirass ventilator. This study is …
 DCPMS: Dialated Cardiomyopathy Precision Medicine Study

DCPMS: Dialated Cardiomyopathy Precision Medicine Study

1-100 years
All genders
This study aims to understand the effects of potential familial/genetic links in an otherwise unclear origin of a patient's heart disease.
 Adaptive Platform Treatment Trial for Outpatients with COVID-19 - ACTIV-2

Adaptive Platform Treatment Trial for Outpatients with COVID-19 - ACTIV-2

18-100 years
All genders
Phase 2
The ACTIV-2 Study is testing an investigational medicine to see if they are safe and can help adults with COVID-19 get better.The type of investigational medicine you might receive in the study is a monoclonal antibody. Antibodies are naturally made by your body to help fight disease. Monoclonal antibodies are …
 Pilot Study of a Multi-System Analysis of Opioid Receptor Binding

Pilot Study of a Multi-System Analysis of Opioid Receptor Binding

18-50 years
All genders
The purpose of this research is to learn more about mu opioid receptor (MOR) binding in the brain and body. This study will enroll up to 60 adults in three cohorts of up to 20 participants each: Cohort 1: Subjects with a lifetime diagnosis of Opioid Use Disorder (OUD) on …
 Testing the Reward-Drinker Hypothesis of Naltrexone Using an Extended-Release Formulation

Testing the Reward-Drinker Hypothesis of Naltrexone Using an Extended-Release Formulation

18-65 years
All genders
Phase 4
This study is being conducted to compare the effects of a medication (extended-release naltrexone or XR-NTX) or placebo (an inactive substance) together with brief counseling on reducing or stopping drinking.   XR-NTX is approved by the U.S. Food and Drug Administration (FDA) for treating alcohol dependence. Its use is experimental …

The OHART Study

18-99 years
All genders
The purpose of this study is to investigate different oral and systemic problems including dental carries, periodontal disease, dry mouth, high cholesterol, diabetes, heart disease, and osteoporosis, observed in patients living with HIV on antiretroviral therapy. 
 Assessing the Impact of Lipoprotein (a) Lowering With TQJ230 on Major Cardiovascular Events in Patients With CVD (Lp(a)HORIZON)

Assessing the Impact of Lipoprotein (a) Lowering With TQJ230 on Major Cardiovascular Events in Patients With CVD (Lp(a)HORIZON)

18-80 years
All genders
Phase 3
This is a pivotal phase 3 study designed to support an indication for the reduction of cardiovascular risk in patients with established CVD and elevated Lp(a)
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