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Found 11 radiation-oncology trials

A listing of radiation-oncology medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

PROPS GYN: ADJUVANT PROTON WHOLE PELVIS RADIATION THERAPY FOR TREATMENT OF POST-SURGICAL GYNECOLOGIC CANCERS

18-99 years
Female
Phase 2
This research study is being done to study the safety and toxicity of proton whole pelvis radiation, a type of external beam radiation treatment, for gynecologic cancers after surgery. Currently, for such gynecology cancers, Image- guided Intensity Modulated Radiation Therapy (IG-IMRT) is being done after hysterectomy as the standard treatment. …
 Circulating Biomarkers for Glioma

Circulating Biomarkers for Glioma

18-99 years
All genders
Subjects will be recruited from the Radiation Oncology and Neurosurgery practices at the Hospital of the University of Pennsylvania. The treating radiation oncologist will determine if the patient is a potential research candidate and has the capacity to consent. The goal of this study is to collect and analyze blood …
 RADVAX FOR RELAPSED/REFRACTORY NON-HODGKIN LYMPHOMA: A PHASE II TRIAL OF PEMBROLIZUMAB + LOW DOSE RADIOTHERAPY

RADVAX FOR RELAPSED/REFRACTORY NON-HODGKIN LYMPHOMA: A PHASE II TRIAL OF PEMBROLIZUMAB + LOW DOSE RADIOTHERAPY

18-99 years
All genders
Phase 2
This study plans to treat subjects with pembrolizumab by infusion in combination with radiation therapy to see if the combination is an effective treatment for relapsed/refractory non-Hodgkin lymphoma. Radiation therapy is commonly used to treat relapsed/refractory non-Hodgkin lymphoma. Although pembrolizumab is FDA-approved for some cancers, including Hodgkin lymphoma, it is …

SBRT with Atezo/Bev for HCC

99 years and younger
All genders
Please see Section 3 of the protocol. Please see Section 3 of the protocol. Please see Section 3 of the protocol.

Project Looking-Glass Evaluation

99 years and younger
All genders
PURPOSE/DESCRIPTION: The overall objective is to evaluate the new CBCT imaging features for radiotherapy CT simulation. The new CBCT images of subjects with malignancies from six disease sites will be compared to their initial conventional CT images used for treatment planning. The primary objective of this study is to determine …

NRG-LU008 Phase III Prospective Randomized Trial of Primary Lung Tumor Stereotactic Body Radiation Therapy Followed by Concurrent Mediastinal Chemoradiation for Locally Advanced Non-Small Cell Lung Cancer.

99 years and younger
All genders
To compare the overall survival in patients with stage II-IIIC inoperable nodepositive non-small cell lung cancer (NSCLC) after image guided, motion-managed conventional radiotherapy to the primary tumor and nodal metastases (Arm 1) or after image guided, motion-managed stereotactic body radiation therapy (SBRT) to the primary tumor followed by conventionally fractionated …

FES in Uterine Cancer

99 years and younger
All genders
Primary Objectives Evaluate utility of FES PET/CT to detect estrogen receptor (ER+) uterine cancer lesions in patients with recurrent or metastatic uterine cancer Secondary Objectives Evaluate utility of FES PET/CT compared to standard axial cross-sectional imaging and/or FDG PET/CT when available to establish tumor heterogeneity and staging Correlate FES uptake …
 SIMCAP (Surgery in Metastatic Carcinoma of Prostate): Phase 2.5 multi-institution randomized prospective clinical trial evaluating the impact of cytoreductive radical prostatectomy combined with best systemic therapy on oncologic and quality of life outcomes in men with newly diagnosed metastatic prostate cancer

SIMCAP (Surgery in Metastatic Carcinoma of Prostate): Phase 2.5 multi-institution randomized prospective clinical trial evaluating the impact of cytoreductive radical prostatectomy combined with best systemic therapy on oncologic and quality of life outcomes in men with newly diagnosed metastatic prostate cancer

18-100 years
All genders
Phase 2
This study investigates the effects of adding cytoreductive radical prostatectomy (CRP) to the standard treatment, best systemic therapy (BST), for metastatic prostate cancer (mPCa). CRP removes as much of the cancer as possible (and radical prostatectomy removes only prostate) while BST uses drugs toxic to cancer cells: chemotherapy and androgen …
 CCTG MA.39: Tailor RT: A Randomized Trial of Regional Radiotherapy in Biomarker Low Risk Node Positive and T3N0 Breast Cancer

CCTG MA.39: Tailor RT: A Randomized Trial of Regional Radiotherapy in Biomarker Low Risk Node Positive and T3N0 Breast Cancer

35 years and older
Female
This study will compare the good and bad effects of not giving regional radiotherapy versus using regional radiotherapy in patients with low risk breast cancer as indicated by Oncotype DX Recurrence Score. This is intended to help researchers discover if not giving regional radiotherapy will be as beneficial as using …

Radiation Oncology Registry and Biosample Repository

18-99 years
All genders
Observational
The goal of this study is to establish a registry and biosample repository (defined as blood, urine, and tumor specimens in patients with a pathologically confirmed diagnosis of neoplasia receiving radiotherapy or photodynamic therapy (PDT). Radiation Oncology Registry (Required): The first part of this study is the Radiation Oncology Registry. …
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