Hormone effects in smoking addiction
The purpose of this study is to determine whether progesterone is helpful in reducing withdrawal symptoms, cigarette cravings, and smoking behavior. This study will also use brain imaging to measure the possible effects of progesterone on your brain chemicals. Healthy male and non-pregnant female smokers are invited to screen for ...
Biobehavioral Effects of Tobacco Labeling and Packaging
This is a study of current smokers' brain responses to tobacco-related images. Eligible participants will be provided with cigarettes at no cost and could earn up to $300. The study includes five weekly visits and 2 functional Magnetic Resonance Imaging (MRI) scans of the brain. MRI uses magnetic fields to ...
RISE (Research in Smoking Elimination)
The main purpose of this research study is to assess how quitting smoking affects memory and attention.
MACS (Mood and Cognition Study)
The main purpose of this research study is to test the effects of an investigational medication on smoking behavior
Effect of Galantamine on Smoking Abstinence
Nicotine dependence is a major public health problem and currently available treatments are ineffective for the majority of smokers. Thus, there is an urgent need to develop and test new medications to aid in smoking cessation. Recent evidence from a genetic study of prospective smoking cessation conducted at the CIRNA ...
A Placebo Controlled Trial of Varenicline for Smoking among those with HIV/AIDS
The main purpose of this research study is to compare the effectiveness of varenicline (brand name Chantix®) to placebo (inactive ingredients) for helping people with HIV/AIDS to quit smoking.
Behavioral Activation and Varenicline for Smoking Cessation in Depressed Smokers
This program involves a study of two different behavioral treatments to help people who have had major depression. If you are eligible for this study, you will be randomly assigned to receive one of two behavioral treatments: either behavioral smoking cessation treatment or behavioral activation smoking cessation treatment. The study ...
Effect of ramelteon on smoking abstinence
There is a need for novel approaches to optimize smoking cessation treatment to help more smokers quit. Sleep disturbance during nicotine withdrawal may be an important treatment target since existing treatments do not mitigate withdrawal-related sleep disturbance and difficulty sleeping predicts smoking relapse. We hypothesize that the FDA-approved melatonin receptor ...
Influence of Hormones on the Brain in Female Smokers with a Regular Menstrual Cycle
The purpose of our research is to examine the influence of hormonal status on brain responses to smoking cues. Magnetic resonance imaging, or MRI, will be used to measure brain responses at three distinct time points during your menstrual cycle, across approximately three separate menstrual cycles. A MRI is a ...
Biomarkers in Neural Disorders
This study is looking at ways to identify people with early Parkinson’s and Alzheimer’s diseases by sensory testing. We are trying to find out if these tests are able tell apart healthy people, people with PD or AD, and people with other neurological diseases.