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Found 11 healthy-controls trials

A listing of healthy-controls medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

 General Screening Protocol for Affected and Unaffected Participants in Studies of Alcohol Use Disorder.

General Screening Protocol for Affected and Unaffected Participants in Studies of Alcohol Use Disorder.

18-75 years
Healthy Volunteer
All genders
The goal is to conduct a screening procedure to be used in evaluating individuals either with or without an alcohol use disorder (AUD) to determine whether it is safe and appropriate for them to participate in a clinical trial, imaging study, genetic study, or other research protocol that matches their …

Advanced Neuroimaging in Multiple Sclerosis

18-65 years
All genders
MS is a life-long disease that can clinically manifest at a wide range of ages. Lesions in the white matter of the brain can be found at any age in MS patients. How these lesions may affect functioning of the brain is an area we aim to explore. Although connections …
 Metabolomic Reprogramming in insomnia as a Function of Objective Sleep Duration

Metabolomic Reprogramming in insomnia as a Function of Objective Sleep Duration

25-50 years
All genders
The research study is being conducted to understand how insomnia and the amount of sleep people get at night affect metabolism. Four groups of people will be asked to participate: individuals with insomnia who sleep >6 hours per night, individuals with insomnia who sleep <6 hours per night, individuals without …
 XCI Maintenance in Scleroderma and Related Female-Biased Diseases

XCI Maintenance in Scleroderma and Related Female-Biased Diseases

35-90 years
All genders
The research study is being done to understand both why and how scleroderma and related female-biased diseases affect women and men differently.  Though we do not know what causes these diseases, we do know that women are much more likely to develop them than men.  We are studying how the …
 Pilot Study of a Multi-System Analysis of Opioid Receptor Binding

Pilot Study of a Multi-System Analysis of Opioid Receptor Binding

18-50 years
All genders
The purpose of this research is to learn more about mu opioid receptor (MOR) binding in the brain and body. This study will enroll up to 60 adults in three cohorts of up to 20 participants each: Cohort 1: Subjects with a lifetime diagnosis of Opioid Use Disorder (OUD) on …
 Kidney Disorders: Biological Specimen Repository and Clinical Database

Kidney Disorders: Biological Specimen Repository and Clinical Database

18-99 years
All genders
To support the research of kidney disorders by creating a bank of biospecimens and a corresponding database of clinical information that will be used for future, unspecified research. Target population is adults with a kidney disorder, but the study also allows for enrollment of family members, healthy controls, and children. …

U19 Amyloid and assessments

All genders
Specific Aims include: Coordinate all human PET and MR imaging at U Penn, UCSF, Yale and WU. Standardize inclusion/exclusion criteria for patient groups - idiopathic PD, MSA, PSP, FTD and healthy controls. Harmonize PET scanning protocols and devices. Generate and coordinate all regulatory protocols including local Radiation Safety or Radioactive …

Analysis of lymphatic fluid from the thoracic duct of healthy subjects and patients with MS before and during Ofatumumab treatment

18-55 years
Healthy Volunteer
All genders
The overall objectives of this study are to evaluate feasibility and safety of thoracic duct sampling, including "in-and-out" cannulation and "indwelling" catheterization in early MS and to compare cellular and signaling markers in thoracic duct lymph compared to measures in the blood, within and across populations of MS patients before …

11C-M503 PET

All genders
Primary Objectives Determine biodistribution of the radioactive investigational drug, 11C M503 and calculate human dosimetry (at least 10 male and female participants). Demonstrate the feasibility of imaging the brain with the novel imaging agent 11C M503 Determine the most appropriate data analysis methodology. Determine whether there is selective uptake of …
 The International MS Microbiome Study

The International MS Microbiome Study

18-90 years
All genders
Dr. Amit Bar-Or, MD, FRCPC from the University of Pennsylvania Department of Neurology is conducting a study to investigate how the structure and activity of gastrointestinal microbes (bacteria and fungi) found in the gut contribute to multiple sclerosis pathogenesis. You are being asked to participate in this study because either …
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