Neurometabolic Assessment of Obstructive Sleep Apnea by MRI
The purpose of this research study is to explore the effect of obstructive sleep apnea (OSA) on brain oxygen metabolism. This will show us how much oxygen your brain uses to function. OSA is known to lower levels of oxygen in the blood and also to cause cognitive deficits. We ...
Risk Evaluation and Education of Alzheimer's Disease - the Study of Communicating Amyloid Neuroimaging
REVEAL-SCAN is a multi-site study funded by the National Institutes of Health, with support from the Alzheimer’s Association. The purpose of the study is to understand how people respond to learning their risk of developing Alzheimer’s disease dementia. Each participant in REVEAL-SCAN receives a personalized estimate of his or her ...
T-Cell Response to Vaccination
The purpose of this study is to see how your body responds to a vaccine and how your body forms a protective response after vaccination. In this study we will use the yellow fever vaccine, an FDA approved vaccine that is commonly given to people traveling to certain parts of ...
A brief treatment on PTSD symptoms in pregnancy
We are looking for women to participate in a research study on psychotherapy for symptoms of Post-Traumatic Stress Disorder (PTSD) during pregnancy. The study will involve: screening questionnaires and a baseline visit to determine eligibility; Participation in a computer based stress task; Four weekly visits (30-45 minutes) with a psychologist ...
Hormone effects in smoking addiction
The purpose of this study is to determine whether progesterone is helpful in reducing withdrawal symptoms, cigarette cravings, and smoking behavior. This study will also use brain imaging to measure the possible effects of progesterone on your brain chemicals. Healthy male and non-pregnant female smokers are invited to screen for ...
Variability in Response to Non-steroidal Anti-inflammatory Drugs
The purpose of this research study is to measure the difference in response to non-steroidal anti-inflammatory drugs (NSAIDs) among people. We will also study what factors, like age, sex, or genetic background, cause these differences.
Paid research study seeking healthy women who are not at risk for pregnancy
The Women’s Health Clinical Research Center at University of Pennsylvania is currently recruiting healthy women who have regular periods for a research study of an investigational injectable birth control. "Investigational" means that it is still being studied and has not been approved by the US FDA. This study will look ...
Investigating the Impact of Childhood Adversity on Brain Activity in Post-Menopausal Women
The aim of this study is to further our understanding of the impact of prepubertal adverse childhood experiences on brain activation during performance of affective and cognitive processing and memory tasks in men post-menopausal women between the ages of 48 and 65. Using functional brain imaging, we will identify differences ...
PTSD Study -- Neuroimaging and Transcranial Magnetic Stimulation (TMS)
We are recruiting individuals who have experienced a life-threatening event for a research study focused on the neuroscience behind depression and post-traumatic stress. Our study uses a mechanism called transcranial magnetic stimulation, or TMS, which is an FDA-approved treatment method for major depression. We are hoping to improve targeting methods ...
Startle Response in Women with Premenstrual Mood Disorders
This study examines stress response in women with premenstrual mood changes. For this study, you will be asked to fill out forms about your physical and mental health, have blood and saliva samples taken, and undergo a test that will measure your stress responses. This is a long-term study, consisting ...