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Found 129 Surgery trials

A listing of Surgery medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Studying imlifidase in comparison to the standard of care in the management of highly sensitized kidney transplant patients.

18-70 years
All genders
Phase 3
Interventional
The purpose of this study is to demonstrate the efficacy and safety of imlifidase in comparison to the standard of care (SoC) in the management of highly sensitized transplant patients.
 A study to assess the safety and tolerability of nebulized PC945 for prophylaxis or pre-emptive therapy against pulmonary aspergillosis in lung transplant recipients.

A study to assess the safety and tolerability of nebulized PC945 for prophylaxis or pre-emptive therapy against pulmonary aspergillosis in lung transplant recipients.

18-99 years
All genders
Phase 2
Interventional
The purpose of this study is to learn about how safe and effective a new investigational drug, PC945, can be. An investigational drug is one that is not approved by the United States Food and Drug Administration (FDA). PC945 is an inhaled drug being studied for the prevention of a …
 Nasal Inhalation Influences on Smell Function

Nasal Inhalation Influences on Smell Function

18-100 years
All genders
The aim of this study is to see whether nasal inhalation can help recover smell loss.Quantitative olfactory testing will be initially performed on the participants.  Such testing will require approximately one hour of the participant’s time. Each participant will subsequently be sent in the mail a box that contains a set of …
 Diabetes Reversal and the Subgingival Microbiota Study

Diabetes Reversal and the Subgingival Microbiota Study

25-65 years
All genders
The Penn Bariatric and Weight Loss Surgery Program at the University of Pennsylvaniais currently seeking individuals who are planning to undergo bariatric surgery andwilling to undergo an oral examination and provide oral samples at study visits beforeand after the surgery. The purpose of this study to determine whether diabetesalters the …
 ADDS-UP3: Interview Study

ADDS-UP3: Interview Study

18-100 years
All genders
Join our ADDS-UP3 (Atopic Dermatitis Disparities Study – University of Pennsylvania & Philadelphia Partnership): Eczema Interview Study!The purpose of this study is to understand your experience living with eczema (also known as atopic dermatitis) and identify the things in your daily life that affect your skin.  Study Details: Your participation in the …

Penn Uterine Transplantation for Uterine Factor Infertility (UNTIL) Trial

21-40 years
Female
The UNTIL Trial is a new clinical research trial that offers uterine transplantation to women with uterine factor infertility (UFI). Participation in this trial requires going through an extensive selection process, creation of embryos through in vitro fertilization, and multiple surgeries. Study participants may remain in the study for 5-10 …
 Prospective  evaluation of the durability of aortic bioprostheses/valves with RESILIA tissue  (RESILIENCE Trial)

Prospective evaluation of the durability of aortic bioprostheses/valves with RESILIA tissue (RESILIENCE Trial)

18-65 years
All genders
The objective of this observational trial is to determine time to valve failure due to valve deterioration requiring re-intervention and collect/investigate early potential predictors of valve durability (e.g., calcification and hemodynamic deterioration) in RESILIA tissue valves.
 TruGraf Long-term Clinical Outcomes Study

TruGraf Long-term Clinical Outcomes Study

18-99 years
All genders
Observational
The purpose of this study is to evaluate post-transplant clinical outcomes in recipients of kidney transplants who are undergoing TruGraf® and TRAC monitoring. These tests are commercially available blood tests that may help better monitor rejection. Targeted population are kidney transplant recipients. Procedures include blood will be drawn for TruGraf® …
 A  study of near infrared imaging of myocardial scar and epicardial ganglionated plexus in patients undergoing cardiac surgery

A study of near infrared imaging of myocardial scar and epicardial ganglionated plexus in patients undergoing cardiac surgery

18-99 years
All genders
Observational
To determine the feasibility of near infrared (NIR) imaging of myocardial scar and epicardial adipose tissue in patients undergoing cardiac surgery.
 DISSECT-N is an Observational Registry to Assess Real-world Safety and Effectiveness of the Valiant Navion Thoracic Stent Graft in Routine Clinical Practice in Subjects Diagnosed With a Dissection of the Thoracic Aorta

DISSECT-N is an Observational Registry to Assess Real-world Safety and Effectiveness of the Valiant Navion Thoracic Stent Graft in Routine Clinical Practice in Subjects Diagnosed With a Dissection of the Thoracic Aorta

18-99 years
All genders
Observational
This is a prospective, observational, global, multi-center, post-market registry intended to assess the real-world safety and effectiveness of the Valiant Navion Stent Graft System in the treatment of thoracic aortic dissections. The primary objective is composite safety and effectiveness at 1-month post-procedure.
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