Language And Cognitive Impairment In Parkinson's Disease
This study is designed to determine the changes in the brain that occur during conditions of verbal stimulation in patients who have Parkinson’s Disease and Parkinson’s Disease with Dementia or Dementia with Lewy Bodies.
Promoting Recovery Optimization with WALKing Exercise after Stroke (PROWALKS)
The goal of this study is to improve walking ability after stroke. The interventions in this study will test whether combining fast walking training with a step activity monitoring program (FAST+SAM) is better in improving real-world walking activity compared to fast walking training alone (FAST) or a step activity monitoring ...
Connected Health Blood Pressure Monitoring In Stroke and TIA Patients (CHAMPS)
This study aims to assess compliance with home blood pressure monitoring in hypertensive patients with a history of stroke to determine if a social incentive improves monitoring. Adult patients who have a history or stroke and uncontrolled hypertension may be eligible for this study. After enrollment, patients will be given ...
Conceptual Processing in Alzheimer’s Disease
The purpose of this study is to evaluate memory, language and cognitive difficulties in patients with AD. AD is a neurological disease where a specific part of the brain is not functioning well. A clinical diagnosis of AD needs to be confirmed in all participants prior to participation in the ...
Risk Evaluation and Education of Alzheimer's Disease - the Study of Communicating Amyloid Neuroimaging
REVEAL-SCAN is a multi-site study funded by the National Institutes of Health, with support from the Alzheimer’s Association. The purpose of the study is to understand how people respond to learning their risk of developing Alzheimer’s disease dementia. Each participant in REVEAL-SCAN receives a personalized estimate of his or her ...
The Impact of individualized network-driven TMS on Language in Post-Stroke Aphasia
The purpose of this research study is twofold: First, we are interested in creating a new framework for characterizing how individuals with post-stroke aphasia are likely to recruit different brain networks during cognitive tasks, especially tasks involving language. Then, we will attempt to use these new network-based predictions on brain ...
Visual Restoration for Hemianopia
This project will collect data to quantify the effect of visual training on visual defects resulting from damage to the primary visual cortex. Subjects will be recruited, undergo baseline visual testing, undergo visual training designed to reduce their visual deficit, and perform post-training visual tests. This research is designed to ...
A PROSPECTIVE RANDOMIZED OPEN-LABEL BLINDED ENDPOINT EVALUATION (PROBE) PARALLEL GROUP STUDY COMPARING EDOXABAN (DU-176B) WITH ENOXAPARIN/WARFARIN FOLLOWED BY WARFARIN ALONE IN SUBJECTS UNDERGOING PLANNED ELECTRICAL CARDIOVERSION OF NONVALVULAR ATRIAL FIBRILLATION
The purpose of this study is to compare edoxaban with warfarin to see if it is safe and effective in preventing thromboembolism (formation of a clot [thrombus] in a blood vessel that breaks loose and is carried by the blood stream to block another vessel) and strokes which results when ...
Cardiovascular Inflammation Reduction Trial (CIRT): A randomized double-blind placebo controlled event-driven trial of weekly low-dose methotrexate (LDM) in the prevention of recurrent cardiovascular events among stable post-myocardial infarction patients with type 2 diabetes or metabolic syndrome
This is an event-driven, multi-center, randomized, double-blind, placebo-controlled trial to determine whether methotrexate reduces heart attacks, strokes, or death in people who have already had at least one heart attack and have type 2 diabetes or metabolic syndrome. Metabolic syndrome is defined as a combination of problems including a large ...
evaluation in persistent atrial fibrillation
The study is expected to be conducted at approximately 40 centers located in Europe, Canada and the United States to support US Food and Drug Administration (FDA) marketing application. A maximum of 350 subjects will be enrolled in the study to ensure 300 subjects can be evaluated for the primary ...