A listing of Retina medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
The primary objective of this study is to determine the prevalence of retinal changes in patients using pentosan polysulfate sodium (PPS) for treatment of interstitial cystitis and further characterize this condition using multimodal imaging. Additionally, this study aims to identify additional clinical findings associated with PPS maculopathy and to gain …
The goal of the NANO trial is to study the longstanding clinical practice of empirically administering intravenous antibiotics to extremely low birthweight (ELBW) infants in the first days of life. In this 802-subject multicenter placebo-controlled randomized clinical trial, the hypothesis to be tested is that the incidence of adverse outcomes …
To evaluate the safety and tolerability of OPGx-001 administered via subretinal injection to one eye (treated eye) of participants with LCA5-IRD. The safety and tolerability as assessed by: 1. Number of dose limiting toxicity (DLT) events at the proposed doses 2. Number of procedure-related adverse events (AEs) 3. Number and …
The primary objective of this observational study is to assess iAMD disease progression, by the timeline and rates of conversion for high-risk iAMD at baseline to more advanced dry AMD stages, such as nascent geographic atrophy (nGA) or incomplete retinal pigment epithelium and outer retinal atrophy (iRORA), and subsequently from …
PURPOSE Record retinal structure with imaging, record visual function, assess change over time and develop a model to predict photoreceptor vulnerability in heterogeneous transition zones of the retina in patients with biallelic ABCA4 mutations and clinical diagnoses of either Stargardt Disease or Cone-Rod Dystrophy. See section 2 'Study Objectives and …
Nearly 20% of children with Neurofibromatosis type 1 (NF1) will develop an optic pathway glioma (OPG), a low-grade glioma that involves one or more structures of the anterior visual pathway (AVP, i.e., optic nerves, optic chiasm and optic tracts). OPGs can cause permanent vision loss which has a significant impact …
The objective of this study is to determine whether visual pathway structure and function correlates with hallucination severity and treatment outcomes in Parkinson disease. The primary outcome variable is hallucination severity, which will be quantified using the PD-adapted Scale for the Assessment of Positive Symptoms (SAPS-PD), a standardized semi-structured instrument …