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Found 8 Retina trials

A listing of Retina medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Evaluating Fenofibrate for Prevention of Diabetic Retinopathy Worsening

18-99 years
All genders
Interventional
This study seeks to find out whether an oral medication called Fenofibrate can slow or prevent worsening of diabetic retinopathy.
 PPS Study- Screening and Classification of Pentosan-Associated Maculopathy in Patients with Interstitial Cystitis

PPS Study- Screening and Classification of Pentosan-Associated Maculopathy in Patients with Interstitial Cystitis

18-99 years
All genders
The primary objective of this study is to determine the prevalence of retinal changes in patients using pentosan polysulfate sodium (PPS) for treatment of interstitial cystitis and further characterize this condition using multimodal imaging. Additionally, this study aims to identify additional clinical findings associated with PPS maculopathy and to gain …
 The NICU Antibiotics and Outcomes Trial (NANO)

The NICU Antibiotics and Outcomes Trial (NANO)

All genders
The goal of the NANO trial is to study the longstanding clinical practice of empirically administering intravenous antibiotics to extremely low birthweight (ELBW) infants in the first days of life. In this 802-subject multicenter placebo-controlled randomized clinical trial, the hypothesis to be tested is that the incidence of adverse outcomes …

Safety and Tolerability of Subretinal OPGx-001 for LCA5-Associated Inherited Retinal Degeneration (LCA5-IRD)

All genders
To evaluate the safety and tolerability of OPGx-001 administered via subretinal injection to one eye (treated eye) of participants with LCA5-IRD. The safety and tolerability as assessed by: 1. Number of dose limiting toxicity (DLT) events at the proposed doses 2. Number of procedure-related adverse events (AEs) 3. Number and …

HONU

All genders
The primary objective of this observational study is to assess iAMD disease progression, by the timeline and rates of conversion for high-risk iAMD at baseline to more advanced dry AMD stages, such as nascent geographic atrophy (nGA) or incomplete retinal pigment epithelium and outer retinal atrophy (iRORA), and subsequently from …

PR disease in IRD - Prospective

All genders
PURPOSE Record retinal structure with imaging, record visual function, assess change over time and develop a model to predict photoreceptor vulnerability in heterogeneous transition zones of the retina in patients with biallelic ABCA4 mutations and clinical diagnoses of either Stargardt Disease or Cone-Rod Dystrophy. See section 2 'Study Objectives and …

GVRI biomarker study 2021

All genders
Nearly 20% of children with Neurofibromatosis type 1 (NF1) will develop an optic pathway glioma (OPG), a low-grade glioma that involves one or more structures of the anterior visual pathway (AVP, i.e., optic nerves, optic chiasm and optic tracts). OPGs can cause permanent vision loss which has a significant impact …

PD psychosis vision

All genders
The objective of this study is to determine whether visual pathway structure and function correlates with hallucination severity and treatment outcomes in Parkinson disease. The primary outcome variable is hallucination severity, which will be quantified using the PD-adapted Scale for the Assessment of Positive Symptoms (SAPS-PD), a standardized semi-structured instrument …