Found 16 Psychiatry trials
A listing of Psychiatry medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
IPS TMS for Patients with PTSD
Phase 1
This study will be the first of its kind to explore the impact of continuous theta burst stimulation (cTBS) to the intraparietal sulcus (IPS) on arousal symptoms among patients with posttraumatic stress disorder (PTSD). We will demonstrate that IPS cTBS results in significant target engagement in the form of reduction …
General Screening Protocol for Affected and Unaffected Participants in Studies of Substance Use Disorders
The goal of this study is to evaluate individuals with and without substance use disorder (SUD) to determine whether it is safe and appropriate for them to participate in a clinical trial, imaging study, or other research protocol that matches the participants’ interests and eligibility. Our goal is to enroll …
Investigation of Social and Circadian Rhythm Dysregulation in the Development of Depression Symptoms During the Menopause Transition
The purpose of this study is to examine how depression symptoms develop when women begin the transition to menopause. This study will investigate depression symptoms by looking at how fluctuations in reproductive hormones (specifically, the hormone estradiol) might impact the body's biological sleep rhythms. This study will also look at …
Metabolomic Reprogramming in insomnia as a Function of Objective Sleep Duration
The research study is being conducted to understand how insomnia and the amount of sleep people get at night affect metabolism. Four groups of people will be asked to participate: individuals with insomnia who sleep >6 hours per night, individuals with insomnia who sleep <6 hours per night, individuals without …
Pilot Study: Establishing Glutamatergic Changes in Rapid Antidepressant Effects of Sleep Deprivation
This study aims to determine what underlies the antidepressant effects of sleep deprivation. A novel measure of glutamate imaging, GluCEST, will be used to assess changes in glutamatergic activity following total sleep deprivation.
Testing the Reward-Drinker Hypothesis of Naltrexone Using an Extended-Release Formulation
Phase 4
This study is being conducted to compare the effects of a medication (extended-release naltrexone or XR-NTX) or placebo (an inactive substance) together with brief counseling on reducing or stopping drinking. XR-NTX is approved by the U.S. Food and Drug Administration (FDA) for treating alcohol dependence. Its use is experimental …
ProNET: Psychosis Risk Outcomes Network
We are seeking young people who are concerned about recent changes in mood, thinking or behavior. This research project aims to increase understanding of mental health concerns in young people and how to prevent the development of a more serious mental illness such as psychosis.
Pilot Study of a Multi-System Analysis of Opioid Receptor Binding
The purpose of this research is to learn more about mu opioid receptor (MOR) binding in the brain and body. This study will enroll up to 60 adults in three cohorts of up to 20 participants each: Cohort 1: Subjects with a lifetime diagnosis of Opioid Use Disorder (OUD) on …
Effects of Nutritional Ketosis on Alcohol Metabolism
The research study is being conducted to better understand the effects of ketosis on brain functioning after three separate 3-day dietary interventions and the acute effects of alcohol during three separate MRI and lab visits after consuming about 4-5 alcohol beverages.
Optimizing Neuromodulation through Individualized Stimulation Frequencies
Transcranial magnetic stimulation (TMS) is a non-invasive mechanism for stimulating brain regions in humans. TMS can potentiate or inhibit activity in various brain regions, and it allows researchers to exert causal control to explore and define network connectivity among brain regions. Using real-time brain readouts combined with interleaved TMS/fMRI, we …
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