Found 5 Proteinuria trials
A listing of Proteinuria medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
LCAT Deficiency Disorders: natural history and identification of biomarkers
Familial lecithin:cholesterol acyl transferase (LCAT) deficiency (FLD) is a rare, hereditary disease with no treatment. It is caused by mutations in the gene for LCAT, an enzyme that is made in the liver and plays a role in the body’s ability to process (“metabolize”) cholesterol. People with FLD have very …
PROTECT- study of the efficacy and safety of sparsentan for the treatment of Immunoglobulin A (IgAN) nephropathy
Phase 3
Immunoglobulin A nephropathy (IgAN) is a rare disease that affects the kidneys, mostly in teens and adults. Kidneys are important to your health because they filter waste materials such as salts, toxins and water out of the blood. The waste is passed out of your body as urine (pee). IgAN …
Boehringer FSGS
This trial explores the efficacy of 3 doses (20 mg, 40 mg, and 80 mg) of BI 764198 with respect to their benefit to lower proteinuria, and investigates the safety, tolerability, and pharmacokinetic and pharmacodynamic profiles of BI 764198 vs placebo.
ORIGIN
Study is enrolling IgAN patients who continue to have persistent proteinuria despite being on RAAS inhibitors for at least 12 weeks. The study intervention is subcutaneous atacicept given once a week. Interested subjects will be taking study drug for up to 96 weeks (36 weeks blinded + 60 weeks open …
TRIDENT 2.0
Primary Objective --To evaluate the hypothesis that the SGLT2 inhibitor, dapagliflozin, alters kidney molecular pathways associated with progression of diabetic kidney disease Secondary Objectives --To evaluate relationships between changes in kidney molecular fingerprints and changes in kidney function --To identify factors associated with changes in kidney molecular fingerprints --To evaluate …
