Found 21 Pediatrics trials
A listing of Pediatrics medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
Adjustable prosthetic sockets for children and adolescents with lower limb loss to accommodate growth
Phase 2
This study aims to develop an adjustable, immediate fit prosthetic device for children age 3- 18 which will accommodate growth. We are looking for children with lower limb amputation- above knee, below knee and symes amputations.All testing will be done within the PM&R Gait Lab located at 1800 Lombard St, …
Pharmacogenetics and Variability In Drug Exposure and Clinical Response to Corticosteroids in Severe BPD
This observational study will follow infants born with a gestational age of less than 32 weeks requiring positive pressure ventilation and planned clinical treatment with corticosteroids for bronchopulmonary dysplasia.
The Whole Health Study: Collaborative Care for OUD and Mental Health Conditions: Randomized Trial
We are interested in comparing 3 care conditions to determine which condition is best to help people with opioid use disorder (OUD) and mental illness reduce their drug use and improve their psychiatric symptoms. The model we are testing is called collaborative care. This model uses a team-based approach in …
The NICU Antibiotics and Outcomes Trial (NANO)
The goal of the NANO trial is to study the longstanding clinical practice of empirically administering intravenous antibiotics to extremely low birthweight (ELBW) infants in the first days of life. In this 802-subject multicenter placebo-controlled randomized clinical trial, the hypothesis to be tested is that the incidence of adverse outcomes …
The Diaphragmatic Initiated Ventilatory Assist (Diva) Trial
DIVA is a pragmatic randomized clinical trial (RCT) to determine: among (P) preterm infants born 24-27 6/7 weeks gestation undergoing extubation from mechanical ventilation, whether (I) Non-invasive neurally adjusted ventilatory assist (NIV-NAVA) (C) compared with Non-synchronized nasal intermittent positive pressure ventilation (NS-NIPPV), will reduce the incidence of (O) extubation failure …
Evaluating the Effect of Sage-718 on Cognitive Function in Participants with Huntington’s Disease
This is a study that evaluates SAGE-718 in participants with Huntington's Disease.
Regional Ventilation DIVA
To compare dependent lung ventilation (as assessed with EIT, vertical center of ventilation (CoV(v)) measure) between extremely preterm infants treated with NIV-NAVA and those treated with NS-NIPPV. To compare global ventilation homogeneity (as assessed with EIT, global inhomogeneity index (GI) measure) between extremely preterm infants treated with NIV-NAVA to those …
A Trial of Endocrine Response in Women with Invasive Lobular Breast Cancer
Phase 2
To study whether fulvestrant is more effective than anastrozole or tamoxifen in reducing Ki67 in ILC and whether that Ki67 reduction will correlate with alterations in expression of ER and ER-regulated genes. Differential Ki67 effect in this study will serve as a surrogate for outcome of ILC patients on endocrine …
Cystic Fibrosis Microbiome
Among lung transplant recipients who survive to 5 years, half suffer from chronic lung allograft dysfunction (CLAD). This study will evaluate how changes in the lung microbiome may cause CLAD in Cystic Fibrosis patients who have been transplanted. This is a case-control study of Cystic Fibrosis lung transplant recipients to …
Longitudinal Assessment of Traumatic Microvascular Injury
The LATMI study uses functional MRI scans to characterize the response of neural blood vessels to increased CO2 levels. TBI patients will undergo assessments and follow up to determine the healing capacity of cerebral vasculature after TBI. Additionally, the study aims to understand the role of endothelial progenitor cells in …
