Found 9 Parkinsonism trials
A listing of Parkinsonism medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
A Open-Label Ascending Dose Study to Evaluate the Safety and Effects of PR001A in Patients With Parkinson's Disease
Phase 1
This is a 5 year study and the purpose is to assess the safety and tolerability of 2 dose levels of PR001A administered via l injection in patients with moderate to severe Parkinson's Disease
Parkinsons Foundation PD GENEration Genetic Registry
This study aims to collect and share Parkinson’s disease genetic testing data from up to 500,000 study participants for research use. Participants will include people with Parkinson's disease (PD) and people at-risk for developing PD, and members of the general community that do not have PD. To investigate the genetic …
Study to Determine the Efficacy and Safety of BIIB122 in Participants with Parkinsons Disease
The LRRK2protein may contribute to disease progression in patients with PD.The study drug (BIIB122) is designed to affect the activity of LRRK2 protein in the brain and may prevent or delay the development of PD symptoms.The main purpose of this study is to look at whether the study drug works …
To identify reliable markers of LRRK2 activity in human CSF.
The purpose of this research study is to evaluate new tests for Parkinson's disease (PD) that may help in developing better treatments.
Bial GBA
I am requesting a reliance agreement with an external IRB The purpose is to investigate the effects, safety, and tolerability of BIA 28-6156. This study is also meant to find out if the effects, safety, and tolerability vary in people with different forms of the GBA1 gene. The ffects will …
The Parkinsons Progression Markers Initiative (PPMI) 2.0 Clinical - Establishing a Deeply Phenotyped PD Cohort
The purpose of this study is to continue to obtain information from people with and without Parkinson disease (PD) so that researchers may better understand how Parkinson disease progresses, in order to inform better treatments. The information collected in this study is for research and not for clinical care. This …
A Study of AAV2-GDNF in Adults with Moderate Parkinsons Disease (REGENERATE-PD)
The study is designed to evaluate the efficacy and safety of intraputaminal delivery of AAV2-GDNF in subjects with moderate Parkinson's disease and demonstrate proof-of-concept. Subjects will be randomized to 1 of 2 treatment arms, AAV2-GDNF surgery or control surgery and will undergo screening, two baseline visits, perioperative procedures, and double-blind …
An extension study to evaluate the long-term efficacy and safety of minzasolmin (UCB0599) in study participants with Parkinsons disease
Subjects currently enrolled in the PD0053 can be enrolled in this study. Subjects will take UCB0599 capsules twice a day at either 180 mg or 360 mg approximately 12 hours apart. The start of the study will overlap with the end of the parent study and run for 30 months …
Study in Parkinson Disease of Exercise
Phase 3
The primary objective is to test whether the progression of the signs of Parkinson's disease is attenuated at 12 months in among persons who have not initiated medication for Parkinson Disease (PD) when they perform high-intensity endurance treadmill exercise.
