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Found 18 Nephropathy trials

A listing of Nephropathy medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

 LCAT Deficiency Disorders: natural history and identification of biomarkers

LCAT Deficiency Disorders: natural history and identification of biomarkers

1-99 years
All genders
Familial lecithin:cholesterol acyl transferase (LCAT) deficiency (FLD) is a rare, hereditary disease with no treatment. It is caused by mutations in the gene for LCAT, an enzyme that is made in the liver and plays a role in the body’s ability to process (“metabolize”) cholesterol. People with FLD have very …
 PROTECT- study of the efficacy and safety of sparsentan for the treatment of Immunoglobulin A (IgAN) nephropathy

PROTECT- study of the efficacy and safety of sparsentan for the treatment of Immunoglobulin A (IgAN) nephropathy

18-99 years
All genders
Phase 3
Immunoglobulin A nephropathy (IgAN) is a rare disease that affects the kidneys, mostly in teens and adults. Kidneys are important to your health because they filter waste materials such as salts, toxins and water out of the blood. The waste is passed out of your body as urine (pee). IgAN …
 A Randomized, Double-Blind, Placebo-Controlled, Phase 3 Study of the Safety and Efficacy of OMS721 in Patients with Immunoglobulin A (IgA) Nephropathy (ARTEMIS-IgAN)

A Randomized, Double-Blind, Placebo-Controlled, Phase 3 Study of the Safety and Efficacy of OMS721 in Patients with Immunoglobulin A (IgA) Nephropathy (ARTEMIS-IgAN)

18-80 years
All genders
Phase 3
This study will use a new investigational study drug called OMS721 in people with Immunoglobulin A (IgA) Nephropathy. This kidney disease produces abnormal amounts of a protein called IgA in the kidney that damage the filtering units or glomeruli. Glomeruli are tiny filtering units in the kidney that remove excess …
 The Nephrotic Syndrome Study Network

The Nephrotic Syndrome Study Network

18-80 years
All genders
The Nephrotic Syndrome Study Network (NEPTUNE) is a multi-disciplinary, multi-center longitudinal observational study. The main purpose of this study is to find markers for progression of Nephrotic Syndrome. We are particularly interested in the diseases called Focal and Segmental Glomerulosclerosis (FSGS), Minimal Change Disease (MCD), and Membranous Nephropathy (MN), which …
 Kidney Disorders: Biological Specimen Repository and Clinical Database

Kidney Disorders: Biological Specimen Repository and Clinical Database

18-99 years
All genders
To support the research of kidney disorders by creating a bank of biospecimens and a corresponding database of clinical information that will be used for future, unspecified research. Target population is adults with a kidney disorder, but the study also allows for enrollment of family members, healthy controls, and children. …
 Continuation of the nuMoM2b Heart Health Study

Continuation of the nuMoM2b Heart Health Study (nuMoM2b-HHS2)

18-99 years
Female
Interventional
The nuMoM2b Heart Health Study (nuMoM2b-HHS) has followed a demographically diverse cohort of women enrolled and richly phenotyped during their first pregnancy, with data and biospecimens prospectively collected for up to 7 years thereafter. The overarching scientific goal of this study is to define the relationship between adverse pregnancy outcomes …
 Study to Evaluate the Efficacy and Safety of Nefecon Treatment in Patients With IgA Nephropathy Who Have Completed Study Nef-301

Study to Evaluate the Efficacy and Safety of Nefecon Treatment in Patients With IgA Nephropathy Who Have Completed Study Nef-301

18-99 years
All genders
Interventional
This is a Phase 3b, multicenter, open-label extension (OLE) study to evaluate the efficacy and safety of Nefecon treatment in patients with IgAN who have completed the Phase 3 Study Nef 301 and continue to be treated with a stable dose of RAS inhibitor therapy (ACEIs and/or ARBs). Patients who …
 Noninvasive Quantification of Renal Oxygen Utilization in Early Kidney Disease

Noninvasive Quantification of Renal Oxygen Utilization in Early Kidney Disease

18-59 years
Healthy Volunteer
All genders
Type 2 diabetes is the most common cause of chronic kidney disease (CKD). In people with diabetes, the kidneys do not function normally and continuously require more oxygen to remove waste from the body. This process, in-turn, depletes the available supply of oxygen, causes damage to the tissue itself, and …
 MRI Quantification of Hipbone Microstructure in Stage 4 and 5 Chronic Kidney Disease (CKD)

MRI Quantification of Hipbone Microstructure in Stage 4 and 5 Chronic Kidney Disease (CKD)

21-100 years
All genders
The purpose of this study is to evaluate hip fracture risk among people with CKD (chronic renal disease/chronic kidney disease) using a new, MRI-based approach.
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