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CureTalks@Penn interviews Penn Medicine physicians about their cutting edge research and clinical trials. Our goal is to inform patients, care-givers, patient advocates and other physicians about research that occurs at Penn Medicine.

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18 "Lung Disease" clinical trials found.

  • A Phase 2 Multicenter, Double-blind, Randomized, Placebo-Controlled Trial to Evaluate Oral Ifetroban in Subjects with Symptomatic Aspirin Exacerbated Respiratory Disease ...

    The primary purpose of this study is to determine the therapeutic effectiveness of Ifetroban to improve sinus and nasal symptoms ...

    Exact  Phase  Laurel Doghramji

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    Exact  Phase  Daniel J Dorgan

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    An extended access program to assess long-term safety of bardoxolone methyl in patients with pulmonary hypertension

    This is a Phase 3a, extended access program to assess long-term safety of bardoxolone methyl in patients with pulmonary hypertension ...

    Exact  Phase  Harold Palevsky Md

  • Open-Labeled Trial Of Zepatier For Treatment Of Hepatitis C-Negative Patients Who Receive Lung Transplants From Hepatitis C-Positive Donors

    There has only been a modest increase in the number of lung transplants each year, increasing from a yearly average ...

    Exact  Phase  David Goldberg

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    Human Respiratory Virome in Health and Lung Disease-Lung Bronchoscopy Cohort

    Humans live in a closely interdependent relationship with microbes that inhabit the human body (the human microbiome), but the viruses ...

    Exact  Phase N/A Ronald Collman Md

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    Intraoperative molecular imaging of pulmonary nodules by BY SGM-101

    Exact  Phase  Sunil Singhal Md

  • UPCC 06518: A Phase 2 Precision Oncology Study of Biomarker-Directed Pembrolizumab-Based Combination Therapy for Advanced Non-Small Cell Lung Cancer

    To evaluate the clinical activity (as assessed by objective response rate [ORR]) pembrolizumab (MK-3475) in combination with MK-4280 or lenvatinib ...

    Exact  Phase  Charu Aggarwal

  • UPCC 09517: Phase II study of Pembrolizumab and Itacitinib (INCB039110) for First Line Treatment of Metastatic Non-Small Cell Lung Cancer ...

    The main purpose of this study is to examine the efficacy of adding itacitinib (also known as INCB039110) to pembrolizumab ...

    Exact  Phase  Joshua Bauml

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    Intratumoral Gene Mediated Cytotoxic Immunotherapy (GMCI) For Resectable Non-Small Cell Lung Cancer

    Surgery is the best treatment for patients with Stage I or II lung cancer; however, nearly 60% of patients have ...

    Exact  Phase  Sunil Singhal Md Charuhas Deshpande Lydia Frenzel Sulyok

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    Pilot study for functional and structural MR Imaging of Endobroncial valve recipients using hyperpoloarized XENON-129

    We propose to use gas Magnetic Resonance Imaging (MRI) using the inhaled contrast agent, hyperpolarized (HP) xenon-129, to study the ...

    Exact  Phase N/A Maurizio Cereda

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