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CureTalks@Penn interviews Penn Medicine physicians about their cutting edge research and clinical trials. Our goal is to inform patients, care-givers, patient advocates and other physicians about research that occurs at Penn Medicine.

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23 "Lung Disease" clinical trials found.

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    An extended access program to assess long-term safety of bardoxolone methyl in patients with pulmonary hypertension

    This is a Phase 3a, extended access program to assess long-term safety of bardoxolone methyl in patients with pulmonary hypertension ...

    profile picture Harold Palevsky Md

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    Intraoperative molecular imaging of pulmonary nodules by BY SGM-101

    profile picture Sunil Singhal Md

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    Human Respiratory Virome in Health and Lung Disease-Lung Bronchoscopy Cohort

    Humans live in a closely interdependent relationship with microbes that inhabit the human body (the human microbiome), but the viruses ...

    profile picture Ronald Collman Md

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    profile picture Daniel J Dorgan

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    Intratumoral Gene Mediated Cytotoxic Immunotherapy (GMCI) For Resectable Non-Small Cell Lung Cancer

    Surgery is the best treatment for patients with Stage I or II lung cancer; however, nearly 60% of patients have ...

    profile picture Sunil Singhal Md profile picture Charuhas Deshpande profile picture Lydia Frenzel Sulyok

  • A Phase 2 Multicenter, Double-blind, Randomized, Placebo-Controlled Trial to Evaluate Oral Ifetroban in Subjects with Symptomatic Aspirin Exacerbated Respiratory Disease ...

    The primary purpose of this study is to determine the therapeutic effectiveness of Ifetroban to improve sinus and nasal symptoms ...

    profile picture Laurel Doghramji

  • UPCC 09517: Phase II study of Pembrolizumab and Itacitinib (INCB039110) for First Line Treatment of Metastatic Non-Small Cell Lung Cancer ...

    The main purpose of this study is to examine the efficacy of adding itacitinib (also known as INCB039110) to pembrolizumab ...

    profile picture Joshua Bauml

  • Open-Labeled Trial Of Zepatier For Treatment Of Hepatitis C-Negative Patients Who Receive Lung Transplants From Hepatitis C-Positive Donors

    There has only been a modest increase in the number of lung transplants each year, increasing from a yearly average ...

    profile picture David Goldberg

  • UPCC 06518: A Phase 2 Precision Oncology Study of Biomarker-Directed Pembrolizumab-Based Combination Therapy for Advanced Non-Small Cell Lung Cancer

    To evaluate the clinical activity (as assessed by objective response rate [ORR]) pembrolizumab (MK-3475) in combination with MK-4280 or lenvatinib ...

    profile picture Charu Aggarwal

  • Functional Lung Avoidance Radiation Therapy Using Hyperpolarized Xenon-129 MRI

    The primary outcomes will be to establish the safety and feasibility of inhaled imaging in patients with NSCLCand to develop ...

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