Found 13 Kidney-Transplant trials
A listing of Kidney-Transplant medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
Studying imlifidase in comparison to the standard of care in the management of highly sensitized kidney transplant patients.
Phase 3
The purpose of this study is to demonstrate the efficacy and safety of imlifidase in comparison to the standard of care (SoC) in the management of highly sensitized transplant patients.
LCAT Deficiency Disorders: natural history and identification of biomarkers
Familial lecithin:cholesterol acyl transferase (LCAT) deficiency (FLD) is a rare, hereditary disease with no treatment. It is caused by mutations in the gene for LCAT, an enzyme that is made in the liver and plays a role in the body’s ability to process (“metabolize”) cholesterol. People with FLD have very …
TruGraf Long-term Clinical Outcomes Study
The purpose of this study is to evaluate post-transplant clinical outcomes in recipients of kidney transplants who are undergoing TruGraf® and TRAC monitoring. These tests are commercially available blood tests that may help better monitor rejection. Targeted population are kidney transplant recipients. Procedures include blood will be drawn for TruGraf® …
NONINTERVENTIONAL EXTENSION STUDY FOR PATIENTS TREATED IN STUDY R5459-RT-1944 WITH REGN5459 OR REGN5458 (BCMA CD3 BISPECIFIC ANTIBODIES) WHO RECEIVE A KIDNEY TRANSPLANT
The primary objective of the study is to assess adverse events (AEs) and serious adverse events (SAEs) in kidney transplant recipients previously treated with REGN5459 or REGN5458 in the R5459-RT-1944 study. The primary endpoint for this study is the incidence of AEs and SAEs over a 12-month period, starting at …
A DOSE ESCALATION AND PROOF-OF-CONCEPT STUDY OF REGN5459 OR REGN5458 (BCMA CD3 BISPECIFIC ANTIBODIES) FOR DESENSITIZATION OF CHRONIC KIDNEY DISEASE PATIENTS IN NEED OF KIDNEY TRANSPLANTATION WHO ARE HIGHLY SENSITIZED TO HUMAN LEUKOCYTE ANTIGEN
Phase 2
Please see Section 2 of the full study protocol. Please see Section 4.1 of the full study protocol Please see Section 4.2 of the full study protocol.
Kidney Transplantation in Recipients and Donors with HIV: Long Term Follow up Study
The purpose of this study is to study how well patients that receive a kidney from an HIV+ organ donor do over 10 years compared to patients that receive a kidney from an HIV- donor. People 18 years of age and older with end-stage renal disease and HIV, and who …
UPCC 12023: Autologous Chimeric Antigen Receptor Engineered T Cell Immunotherapy for Desensitization in Patients Awaiting Kidney Transplantation
Please refer to Protocol Section 2 (Study Hypothesis/Objectives). Please refer to Protocol Section 3.5 (Primary Endpoints). Please refer to Protocol Section 3.6 (Secondary Endpoints).
A trial of transplanting Hepatitis C-viremic kidneys into Hepatitis C-Negative kidney recipients
Phase 2
The THINKER-NEXT research study is being done to determine whether it is safe to give a kidney transplant from a donor with hepatitis C to a patient without hepatitis C. The recipient will then be given a drug called Epclusa for 12 weeks to treat hepatitis C. Patients who are …
IMAGINE (Interleukin 6 Blockade Modifying Antibody-Mediated Graft INjury and eGFR Decline)
Evaluate efficacy and safety of clazakizumab in preventing allograft loss in kidney transplant recipients. See section 3.1 of protocol. See section 3.2 of protocol.
Memo Safe Kidney II
This is a pivotal phase II/III, randomized, double-blind, placebo-controlled study designed to evaluate the safety, tolerability, and efficacy of AntiBKV in KTRs (kidney transplant recipients).
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