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Found 33 High blood pressure trials

A listing of High blood pressure medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

 Early Diagnosis of TTR Amyloid

Early Diagnosis of TTR Amyloid

40-75 years
All genders
Interventional
The purpose of this study is to find out if we can detect a disease of the heart called cardiac transthyretin (TTR) amyloidosis early. People develop cardiac TTR amyloidosis due to an accumulation of a transthyretin protein in the heart. This can happen as part of an aging process (wild …
 XCI Maintenance in Scleroderma and Related Female-Biased Diseases

XCI Maintenance in Scleroderma and Related Female-Biased Diseases

35-90 years
All genders
The research study is being done to understand both why and how scleroderma and related female-biased diseases affect women and men differently.  Though we do not know what causes these diseases, we do know that women are much more likely to develop them than men.  We are studying how the …

The OHART Study

18-99 years
All genders
The purpose of this study is to investigate different oral and systemic problems including dental carries, periodontal disease, dry mouth, high cholesterol, diabetes, heart disease, and osteoporosis, observed in patients living with HIV on antiretroviral therapy. 
 A Randomized, Double-Blind, Placebo-Controlled, Phase 3 Study of the Safety and Efficacy of OMS721 in Patients with Immunoglobulin A (IgA) Nephropathy (ARTEMIS-IgAN)

A Randomized, Double-Blind, Placebo-Controlled, Phase 3 Study of the Safety and Efficacy of OMS721 in Patients with Immunoglobulin A (IgA) Nephropathy (ARTEMIS-IgAN)

18-80 years
All genders
Phase 3
This study will use a new investigational study drug called OMS721 in people with Immunoglobulin A (IgA) Nephropathy. This kidney disease produces abnormal amounts of a protein called IgA in the kidney that damage the filtering units or glomeruli. Glomeruli are tiny filtering units in the kidney that remove excess …
 The Nephrotic Syndrome Study Network

The Nephrotic Syndrome Study Network

18-80 years
All genders
The Nephrotic Syndrome Study Network (NEPTUNE) is a multi-disciplinary, multi-center longitudinal observational study. The main purpose of this study is to find markers for progression of Nephrotic Syndrome. We are particularly interested in the diseases called Focal and Segmental Glomerulosclerosis (FSGS), Minimal Change Disease (MCD), and Membranous Nephropathy (MN), which …
 Continuation of the nuMoM2b Heart Health Study

Continuation of the nuMoM2b Heart Health Study (nuMoM2b-HHS2)

18-99 years
Female
Interventional
The nuMoM2b Heart Health Study (nuMoM2b-HHS) has followed a demographically diverse cohort of women enrolled and richly phenotyped during their first pregnancy, with data and biospecimens prospectively collected for up to 7 years thereafter. The overarching scientific goal of this study is to define the relationship between adverse pregnancy outcomes …

Noninvasive Subharmonic Aided Pressure Estimation of Portal Hypertension

All genders
Determine the reproducibility of the subharmonic aided pressure estimation (SHAPE) algorithm in subjects to estimate portal pressures with an ultrasound scanner. Examine if serial SHAPE can accurately predict development of ascites and other liver related events. Use SHAPE to monitor treatment response in patients identified with portal hypertension and compare …
 A Randomized Study to Compare Efficacy  Safety  and Tolerability of Macitentan 75mg Versus Macitentan 10mg in Patients with Pulmonary Arterial Hypertension  Followed by an Open-label Treatment Period with Macitentan 75mg

A Randomized Study to Compare Efficacy Safety and Tolerability of Macitentan 75mg Versus Macitentan 10mg in Patients with Pulmonary Arterial Hypertension Followed by an Open-label Treatment Period with Macitentan 75mg

18-75 years
All genders
Phase 3
TThe research study is being conducted to compare macitentan 75 mg with the approved macitentan 10 mg to see if it is well tolerated, safe and useful for treating patients with pulmonary arterial hypertension (PAH).

The RADIANCE II Pivotal Study A Study of the ReCor Medical PARADISE System in Stage II Hypertension

All genders
Phase 3
The purpose of this clinical study is to see whether a medical device called the Paradise Renal Denervation System (also called The Paradise System) can lower high blood pressure in patients who are known to have hypertension. The results of this study will be used to help the Food and …

Pulmonary Vascular Complications of Liver Disease 3

18-99 years
All genders
The main purpose of this study is to determine if certain genes, hormones, or other factors predict the risk of developing lung vessel disease in patients with liver disease and whether they determine outcome. Patients in need of a liver transplant evaluation or have portopulmonary hypertension or are suspected of …
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