Found 30 Hematology trials
A listing of Hematology medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
Mismatched Unrelated Donor Hematopoietic Cell Transplantation With Post-Transplantation Cyclophosphamide (ACCESS)
This is a prospective, multi-center, Phase II study of hematopoietic cell transplantation using human leukocyte antigen-mismatched unrelated donors for peripheral blood stem cell transplant in adults and bone marrow stem cell transplant in children.
LCAT Deficiency Disorders: natural history and identification of biomarkers
Familial lecithin:cholesterol acyl transferase (LCAT) deficiency (FLD) is a rare, hereditary disease with no treatment. It is caused by mutations in the gene for LCAT, an enzyme that is made in the liver and plays a role in the body’s ability to process (“metabolize”) cholesterol. People with FLD have very …
PMBB ROR Program
The goal of the proposed research is to conduct a Hybrid Type 1 effectiveness-implementation study59 to evaluate eHealth delivery alternatives for pre-disclosure education and return of actionable genetic research results. Aim 1 (Effectiveness of eHealth return of results): To evaluate in a randomized study whether disclosure of actionable genetic results …
ASH RC Data Hub
The ASH Registry d/b/a the ASH Research Collaborative (ASH RC), is a non-profit organization established by the American Society of Hematology (ASH) in 2018 that aims to improve the lives of those affected by blood diseases by fostering collaborative partnerships to accelerate progress in hematology. The s Data Hub, a …
MEAK
Primary: to evaluate the safety and tolerability of single doses of AUT00201 in patients with MEAK. Secondary: -To characterize the correlation of exposure to AUT00201 with effects on measures of cortical inhibition, as assessed by paired-pulse transcranial magnetic stimulation (TMS), in patients with MEAK -To assess the pharmacokinetic (PK) profile …
UPCC 28422 An Open-Label, Phase I Study To Evaluate The Safety, Pharmacokinetics And Preliminary Anti-Tumor Activity Of Ro7227166 (A Cd19 Targeted 4-1bb Ligand) In Combination With Obinutuzumab And In Combination With Glofitamab Following A Pre-Treatme
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UPCC 45421 Phase I/II study to reduce post-transplantation cyclophosphamide dosing for older or unfit patients undergoing bone marrow transplantation for hematologic malignancies
Certain blood cancers are treat blood or bone marrow transplants. Sometimes the donor cells attack the recipient's body, called GVHD. Cyclophosphamide helps reduce the risk and severity of GVHD .Researchers want to learn if using a lower dose of cyclophosphamide may reduce the drug's side effects while maintaining its effectiveness.
AZA-MDS-006: Connect Myeloid: The Myelofibrosis (MF), Myelodysplastic Syndromes (MDS) and Acute Myeloid Leukemia (AML) Disease Registry
The purpose of the Connect Myeloid disease registry is to provide unique insights into treatment decisions and treatment patterns as they relate to clinical outcomes of patients with myeloid diseases in routine clinical practice. This disease registry will also evaluate molecular and cellular markers that may provide further prognostic classification …
Study of INO-5401 Alone or INO-5401 in Combination with INO-9012 Followed by Electroporation in Adults with BRCA1 or BRCA2 Mutations
Phase 1
The research study is being conducted to test an experimental vaccine to potentially prevent cancer for people with BRCA1 or BRCA2 mutations. This study will test if the vaccine is safe (without significant side effects) and test a new way of administering vaccines. It will also test whether the vaccine …
