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Found 3 Gliomas trials

A listing of Gliomas medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

A Phase 2 Trial Of All-Trans Retinoic Acid (ATRA) Plus PD-1 Inhibition In Recurrent IDH-Mutant Glioma

All genders
Phase 2
The purpose of this research study will be to evaluate the safety and effectiveness of two investigational drugs, All-trans retinoic acid (ATRA) and Retifanlimab (anti-PD1 monoclonal antibody), in treating recurrent IDH-mutant gliomas. Objective radiographic response (CR + PR + MR) using Response Assessment in Neuro-Oncology (RANO) criteria by measurable disease …
 Circulating Biomarkers for Glioma

Circulating Biomarkers for Glioma

18-99 years
All genders
Subjects will be recruited from the Radiation Oncology and Neurosurgery practices at the Hospital of the University of Pennsylvania. The treating radiation oncologist will determine if the patient is a potential research candidate and has the capacity to consent. The goal of this study is to collect and analyze blood …

GVRI biomarker study 2021

All genders
Nearly 20% of children with Neurofibromatosis type 1 (NF1) will develop an optic pathway glioma (OPG), a low-grade glioma that involves one or more structures of the anterior visual pathway (AVP, i.e., optic nerves, optic chiasm and optic tracts). OPGs can cause permanent vision loss which has a significant impact …