Found 10 Dementia trials
A listing of Dementia medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
A Study to Evaluate Efficacy and Safety of Treatment With Lecanemab in Participants With Preclinical Alzheimer's Disease and Elevated Amyloid and Also in Participants With Early Preclinical Alzheimer's Disease and Intermediate Amyloid
Phase 3
The Study is two research trials aimed at preventing Alzheimer’s disease (AD) dementia. One is called AHEAD-3 and the other is called AHEAD-45. AHEAD-3 studies people with intermediate amyloid, while AHEAD-45 studies people with elevated amyloid. Research studies are designed to gain scientific knowledge that may help people in the …
A Phase 1/2 Ascending Dose Study to Evaluate the Safety and Effects on Progranulin Levels of PR006A in Patients with Fronto-Temporal Dementia with Progranulin Mutations (FTD-GRN)
Phase 2
Evaluate the safety, tolerability, and immunogenicity of 3 dose levels of PR006A administered via sub-occipital injection into the cisterna magna and Quantify PGRN levels in blood and CSF. Please refer to section 2 of the attached protocol. Please refer to section 2 of the attached protocol.
Diverse Vascular Contributions to Cognitive Impairment and Dementia (Diverse VCID): White Matter Lesion Etiology of Dementia in Diverse Populations
The purpose of this study is to better understand how blood vessel health impacts your thinking. The study is interested in the brains white matter, which is involved in the movement of messages and impulses throughout the brain. The study is run out of the University of California Davis and …
PBFT02-001- Phase 1B Study to Assess a Single Dose of PBFT02 Delivered into Adult Subjects with Fronto-Temporal Dementia (FTD) and Mutations in the Progranulin Gene (GRN)
Phase 1
This research is being done to study a new way to treat FTD in patients who have the GRN mutation. This process is called “gene therapy”. Gene therapy is an experimental technique that aims to replace the gene that is not working properly with a version of the gene that …
011
This work will provide a means for estimating the prevalence of dementia and Mild Cognitive Impairment for India that can be adapted to other harmonized surveys of aging in developing countries. The longitudinal nature of the project will provide insight on deterioration of cognitive abilities among the aged over time. …
Clinical Core Alzheimer's Disease Core Center (ABC)
The study is at the Penn Memory Center at the University of Pennsylvania and is under the direction of David Wolk, M.D.. We are currently recruiting normal control participants ages 75 years and older. The purpose of this study is to collect, store and analyze cognitive data and biological samples, …
Brain Arterio-Venous Metabolomic Profiling
The research study is being conducted to better understand brain metabolism, i.e. how the brain uses and consumes the various nutrients that are available in the blood. Changes in brain metabolism have been implicated in dementia and psychiatric disorders, as well as short- and long-term outcomes of traumatic brain injury …
Healthy volunteers for Neuroinflammatory research study
We are conducting research studies on how immune system cells contribute to inflammatory conditions of the nervous system, such as multiple sclerosis, neuromyelitis optica (NMO), encephalitis, head injury, epilepsy, Parkinson's disease (PD), Alzheimer's disease (AzD), Lou Gherig's disease (amyotrophic lateral sclerosis; ALS) frontotemporal dementia (FTD) and others. This includes investigating …
ARTFL LEFFTDS Longitudinal Frontotemporal Dementia Study (ALLFTD)
The purpose of this study (ALLFTD) is to understand how Frontotemporal Lobar Degeneration (FTLD) syndromes progress over time, and to develop new tools to help with diagnosis and eventual treatment. The study is enrolling patients with FTLD syndromes. Additionally, the study is enrolling healthy members of families where there is …
Phenotype Genotype and Biomarkers 2 (PGB2)
The purpose of this study is to learn more about amyotrophic lateral sclerosis (ALS) and other related neurodegenerative diseases, including frontotemporal dementia (FTD), primary lateral sclerosis (PLS), hereditary spastic paraplegia (HSP), progressive muscular atrophy (PMA) and multisystem proteinopathy (MSP). More precisely, we want to identify the links that exist between …
