Determination of B-cell responsiveness to the incretin hormones GLP-1 and GIP in Cystic Fibrosis (PRIME)
The mechanisms underlying cystic fibrosis related diabetes (CFRD) pathophysiology must be better defined if care for people with CFRD is to be optimized or if development of CFRD is to be interrupted. Detailed studies of insulin secretion in CF are required to achieve this goal since 1) subtle insulin secretion ...
Cystic Fibrosis' response to incretin hormone treatment
This study investigates how the CF population with impaired glucose tolerance responds to acute treatment with incretin hormones.
Effectiveness of sitagliptin in Cystic Fibrosis with impaired glucose tolerance
This study will evaluate how effective sitagliptin, a DPP-IV inhibitor, is at improving glycemic control in the Cystic Fibrosis population.