Found 16 Cardiomyopathy trials
A listing of Cardiomyopathy medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
DCPMS: Dialated Cardiomyopathy Precision Medicine Study
This study aims to understand the effects of potential familial/genetic links in an otherwise unclear origin of a patient's heart disease.
A Study to Evaluate Patients with TransthyretinMediated Amyloid Cardiomyopathy (ATTR CM)
Phase 3
This study is for those diagnosed with transthyretin-mediated amyloid cardiomyopathy which is a disease caused by change in a protein called transthyretin (TTR). This change can either be sporadic which is known as wild-type (wtATTR-CM) or due to a mutation of the TTR gene which is hereditary (hATTR-CM). In both …
Insights in Hypertrophic Cardiomyopathy and Observational Outcomes in Real World (DISCOVER-HCM)
Phase 4
The purpose of this registry is to understand the safety and effectiveness of various medications used in treating the condition of symptomatic obstructive hypertrophic cardiomyopathy (HCM), a type of heart disease that causes the muscular wall in the chambers of the heart to thicken which can cause blood flow in …
Expanded Access Protocol to Provide Patisiran to Patients with Transthyretin-mediated Amyloidosis (ATTR Amyloidosis) with Cardiomyopathy
This patisiran expanded access protocol (EAP) is an open-label, multicenter, single-arm study designed to provide pre-approval access to investigational patisiran for patients with ATTR amyloidosis with cardiomyopathy who, at baseline, have an inadequate response to or cannot tolerate standard of care. An intravenous infusion of study drug (patisiran 0.3 mg/kg) …
MARVEN: Clinical, Electrocardiographic, and Cardiac Magnetic Resonance Imaging Risk Factors Associated with Ventricular Tachyarrhythmias in Nonischemic Cardiomyopathy
The purpose of this study is to learn what clinical, cardiac magnetic resonance imaging (CMR), and ECG factors could better identify which nonischemic cardiomyopathy (NICM) patients might develop rapid irregular heartbeats. This would then better identify who needs to get a CRT-D device. The study enrolls patients with NICM whose …
INFINITY-Prospective Cohort Study of Mechanistic Associations between Intra-Myocardial Fat Deposition and Ventricular Tachycardia in Ischemic Cardiomyopathy
This study will focus on fat buildup inside the heart muscle, a newly recognized factor that makes patients vulnerable to such fast heart rates, or ventricular tachycardia, after a heart attack. This work may identify more successful strategies for curing dangerously fast heart rates. Adult subjects with prior history of …
AN OPEN-LABEL STUDY OF CK3773274 FOR PATIENTS WITH SYMPTOMATIC HYPERTROPHIC CARDIOMYOPATHY (HCM) AND LEFT VENTRICULAR OUTFLOW TRACT OBSTRUCTION
Phase 2
PURPOSE/DESCRIPTION: This is an open label trial to collect long-term safety and tolerability data, including assessments of cardiac structure and function, during chronic dosing with CK3773274. A cardiac magnetic resonance (CMR) imaging sub-study will assess the effects of long-term dosing on cardiac morphology, function and fibrosis.
NONCOMPACT- International Consortium for Multimodality Phenotyping in Adults with Non-compaction
This is a prospective, multicenter observational study to identify clinical, genetic and imaging predictors of clinical outcome in patients with suspected non-compaction cardiomyopathy Many healthy people have increased trabeculations without consequences, however, some may develop blood clots, heart rhythm disorders or heart failure later in life. Currently we cannot predict …
SHaRE Registry
This study aims to identify genotypic and phenotypic characteristics that are associated with the clinical heterogeneity and outcomes of hypertrophic cardiomyopathy (HCM), using the Sarcomeric Human Cardiomyopathy Registry (SHaRe).
1 - 10 of 16
- 1
- 2
