Found 10 Anxiety trials
A listing of Anxiety medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
IPS TMS for Patients with PTSD
Phase 1
This study will be the first of its kind to explore the impact of continuous theta burst stimulation (cTBS) to the intraparietal sulcus (IPS) on arousal symptoms among patients with posttraumatic stress disorder (PTSD). We will demonstrate that IPS cTBS results in significant target engagement in the form of reduction …
Resting State Changes Following Theta Burst Stimulation (TBS/rsFC)
This research study is being conducted to learn more about how brain stimulation [transcranial magnetic stimulation (TMS)] affects the communication between brain regions. TMS is a new treatment that is starting to be used to treat depression and other psychiatric disorders. However, we do not have a good idea for …
Neuropsychiatric sequalae of COVID-19
The purpose of this study is to explore possible neurological complications resulting from prior COVID-19 infection. Neurological symptoms, including ‘brain fog’, depression, and/or anxiety can be disabling. This study aims to determine the prevalence and severity of these symptoms. Unfortunately, little is known about these neuropsychiatric symptoms, particularly in patients …
A Double-Blinded Randomized Crossover Trial of Stereoencephalography-Guided Multi-Lead Deep Brain Stimulation for Treatment-Refractory Obsessive Compulsive Disorder (SEEG-Guided DBS for OCD)
Phase 1
This dual-site, double-blinded, randomized, sham-controlled, crossover study is to assess the safety, feasibility, and preliminary efficacy of SEEG-guided multi-lead DBS in 10 participants suffering from severe symptoms of chronic, treatment-refractory OCD. Stage 1: Invasive SEEG Monitoring and Recovery Goal: To perform stimulation mapping studies and SEEG recordings, that aid in …
Examining the mechanisms of anxiety regulation using a novel, sham-controlled, fMRI-guided rTMS protocol and a translational laboratory model of anxiety
This research study is being conducted to learn more about how brain stimulation [transcranial magnetic stimulation (TMS)] affects fear and anxiety through memory and attention tasks. We hope to better understand brain processes related to fear and anxiety. If you agree to join the study, you will be asked to …
An Exposure-Based Implementation Strategy to Decrease Clinician Anxiety about Delivering Suicide Prevention Evidence-Based Practices
This is one of three exploratory projects through the Penn INSPIRE Center grant. The study aims to design and pilot-test an evidence-based implementation strategy (EBIS) to target clinician-level anxiety when screening, assessing, and intervening with patients at risk for suicide. EBIS will be developed through rapid cycle prototyping with community …
A pilot randomized control trial to determine the feasibility of a hypnosis intervention for the treatment of bladder pain syndrome/interstitial cystitis.
The purpose of this research study is determine the feasibility of a hypnosis intervention to women with bladder pain syndrome. We also plan to assess the effect of hypnotic words and suggestions on brain function. Hypnotherapy has been studied in other chronic pain conditions and has been shown to be …
Developing a Cultural Adaptation Toolkit to Increase Equity for Underserved Youth with Obsessive-Compulsive and Related Disorders
Improving the quality of evidence-based interventions (EBIs) for pediatric obsessive-compulsive disorder (OCD) and anxiety disorders for underserved youth is a critical step in reducing mental health care inequities. Youth of color and low-income youth have been impacted by systemic and structural inequities (e.g., racism and discrimination, lack of access to …
PTSD Treatment Study
Phase 2
Have you experienced a traumatic event that affected your life significantly? You may be eligible to participate in a study conducted by the Center for the Treatment and Study of Anxiety at the University of Pennsylvania.In this study we will investigate the influence of gonadal hormones on fear acquisition and extinction …
Harnessing Hormonal Variation to Probe Neural Mechanisms of OCD and Symptom Reduction by EX/RP
Studies show that hormones affect the brain’s fear extinction network, which is relevant for therapy involving exposure and ritual prevention (EX/RP), a first-line treatment for obsessive compulsive disorder (OCD). This study will examine the effect of delivering EX/RP to women during different phases in their menstrual cycle to determine the effects of hormones on the …
