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Found 12 Addictions trials

A listing of Addictions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

 General Screening Protocol for Affected and Unaffected Participants in Studies of Alcohol Use Disorder.

General Screening Protocol for Affected and Unaffected Participants in Studies of Alcohol Use Disorder.

18-75 years
Healthy Volunteer
All genders
The goal is to conduct a screening procedure to be used in evaluating individuals either with or without an alcohol use disorder (AUD) to determine whether it is safe and appropriate for them to participate in a clinical trial, imaging study, genetic study, or other research protocol that matches their …
 General Screening Protocol for Affected and Unaffected Participants in Studies of Substance Use Disorders

General Screening Protocol for Affected and Unaffected Participants in Studies of Substance Use Disorders

18-64 years
All genders
The goal of this study is to evaluate individuals with and without substance use disorder (SUD) to determine whether it is safe and appropriate for them to participate in a clinical trial, imaging study, or other research protocol that matches the participants’ interests and eligibility. Our goal is to enroll …
 Testing the Reward-Drinker Hypothesis of Naltrexone Using an Extended-Release Formulation

Testing the Reward-Drinker Hypothesis of Naltrexone Using an Extended-Release Formulation

18-65 years
All genders
Phase 4
This study is being conducted to compare the effects of a medication (extended-release naltrexone or XR-NTX) or placebo (an inactive substance) together with brief counseling on reducing or stopping drinking.   XR-NTX is approved by the U.S. Food and Drug Administration (FDA) for treating alcohol dependence. Its use is experimental …

Opioid and Brain Study

18-60 years
All genders
Have problem with opiates? You may qualify for the study if you are:    - Between 18–60 years old    - In treatment or seeking treatment for opioid use problems    - Willing to complete one MRI scan of the brain  The study will investigate the psychological and brain mechanisms of opioid use disorder. There will be …
 Pilot Study of a Multi-System Analysis of Opioid Receptor Binding

Pilot Study of a Multi-System Analysis of Opioid Receptor Binding

18-50 years
All genders
The purpose of this research is to learn more about mu opioid receptor (MOR) binding in the brain and body. This study will enroll up to 60 adults in three cohorts of up to 20 participants each: Cohort 1: Subjects with a lifetime diagnosis of Opioid Use Disorder (OUD) on …
 Neurobiology of Caregiving in New Mothers (Children between 0-3 years old)

Neurobiology of Caregiving in New Mothers (Children between 0-3 years old)

1-42 years
Female
This study is to learn more about social processes on a behavioral and brain level in new mothers. If you are eligible, there are three in person visits, one consisting of an fMRI scan. MRI uses magnetic fields to take pictures of the brain. MRI does not use X-rays and …

Effects of Nutritional Ketosis on Alcohol Metabolism

21-50 years
Healthy Volunteer
All genders
The research study is being conducted to better understand the effects of ketosis on brain functioning after three separate 3-day dietary interventions and the acute effects of alcohol during three separate MRI and lab visits after consuming about 4-5 alcohol beverages.
 HVTN 144: A Clinical Trial to Evaluate Whether A Study Drug Increases Immunity in Adult Participants without HIV

HVTN 144: A Clinical Trial to Evaluate Whether A Study Drug Increases Immunity in Adult Participants without HIV

18-55 years
Healthy Volunteer
All genders
Phase 1
The HIV Vaccine Trials Network (HVTN) and the study site are doing a study to test an experimental HIV vaccine with an experimental adjuvant.

LFX-PGB Opioid Outpatient Withdrawal

All genders
This study will examine the safety and effectiveness of lofexidine/pregabalin compared to lofexidine/placebo for managing opioid withdrawal in an outpatient settings. The study timeline is Screening from 1-30 days; dosing for 1-7 days, and a sttudy medication taper on days 8, 9, 10; Day 8 is also 1st dose of …

Caron Ketone AUD withdrawal study

All genders
To examine the effects of ketone supplement, Kenetik (KS) three times daily (TID), verse placebo, on the need for benzodiazepines and CIWA scores, while undergoing in-patient acute withdrawal management.To test the effects of Ketone Supplementation (KS) Kenetik in reducing alcohol withdrawal signs and symptoms and the need for medications to …
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