Stress and Inflammation in Depression
The goal of this study is to understand the effects of inflammation on the aging brain. We want to learn if depression over a person’s lifetime is related to the amount of inflammation in the brain and whether the amount of inflammation in the brain affects treatment response. We also ...
A Study Examining the Effectiveness of an FDA-Approved Medication for the Treatment of Binge Eating Disorder
The 17-week, double-blind, randomized placebo-controlled trial will test the efficacy of an FDA-approved medication, liraglutide 3.0 mg/d, as compared to placebo in reducing the number of binge episodes per week, achieving remission from binge episodes, and in changes in body weight, global BED symptom improvement, and other psychological factors related ...
A study to understand how the brain develops and changes in people ages 10 - 30
The purpose of this study is to examine the brain and behavior as it relates to development and genetics in men and women ages 10 – 30 years old. The project will enroll three study groups: individuals with schizophrenia, individuals at clinical risk for developing psychosis, and healthy controls.
A Phase II Randomized Double-Blind Trial of Varenicline for the Treatment of Cocaine Dependence
This is a double-blind placebo-controlled clinical trial (n = 200) of varenicline for the treatment of cocaine dependence that utilizes contingency management to promote treatment attendance. Participants will be randomized (1:1) to receive varenicline (1.0 mg BID) for 12 weeks. Primary outcome measures include biochemically verified cocaine and nicotine use.
Weight History, Brain Activation to Food Cues and Eating Disorder Psychopathology
Drexel University and the University of Pennsylvania seek women exhibiting eating disordered behaviors for studies funded by NIH. Studies examine biological, neurological, and behavioral factors contributing to eating problems. Eligible participants attend four to five visits over six months. Compensation is provided. Call 215-762-1313 or e-mail DUeatingdisorders@drexel.edu
Serenity Study: Lowering High Blood Pressure with Stress Management Techniques
The Serenity Study is a voluntary research study that will investigate different approaches to stress management in order to help lower blood pressure. You may be eligible to participate if you: have blood pressure in the pre-hypertensive range (systolic BP 120-139 or diastolic BP 80-89), are a healthy adult between ...
Child Nutrition Study
The University of Pennsylvania is seeking children (ages 7 to 9) and their mother to participate in a nutrition research study. Children will be asked to eat breakfast, lunch, and dinner in our center once a week for two weeks. Each visit will last from 8:00AM until 5:30PM. Children will ...
Behavioral Activation and Varenicline for Smoking Cessation in Depressed Smokers
This program involves a study of two different behavioral treatments to help people who have had major depression. If you are eligible for this study, you will be randomly assigned to receive one of two behavioral treatments: either behavioral smoking cessation treatment or behavioral activation smoking cessation treatment. The study ...
A brief treatment on PTSD symptoms in pregnancy
We are looking for women to participate in a research study on psychotherapy for symptoms of Post-Traumatic Stress Disorder (PTSD) during pregnancy. The study will involve: screening questionnaires and a baseline visit to determine eligibility; Participation in a computer based stress task; Four weekly visits (30-45 minutes) with a psychologist ...
Randomized, Double Blind, Placebo-Controlled Trial of the Safety and Efficacy of HORIZANT® (Gabapentin Enacarbil) Extended-Release Tablets for the Treatment of Alcohol Use Disorder
Alternating phone and in-clinic visits for medical management (MM), laboratory tests, and physical exams, to assess drug compliance, to complete additional questionnaires, and to provide counseling (via “Take Control” videos) over 29 weeks.