Study to Investigate Drug BIIB132 Administered to Adults With Spinocerebellar Ataxia 3

Study Overview

The purpose of this research study is to learn more about a study drug that may affect patients with spinocerebellar ataxia type 3 (SCA3). This type of drug is called an antisense oligonucleotide. Eligible participants in this study will have the study drug injected into the fluid surrounding their spinal cord and brain through a fine needle placed in the spinal canal in the lower back. This procedure is called a lumbar puncture. After injection of the study drug, participants will be monitored in the hospital for 6 to 24 hours before going home. During the study, participants will receive study drug at up to 4 visits. Some of the assessments include: examinations of the brain and body, collection of blood, urine, and CSF (the fluid in the spine) samples, medical scans of the brain, and questionnaires about health and daily life.

  • Study Identifier: 850137

Recruitment Status


Contact the research team to learn more about this study.

Fields marked with asterisk (*) are required

Please verify that you are not a bot.

By clicking "Contact Research Team", your contact information will be sent securely to the research staff associated with the study. You will also receive a copy of this email in your inbox, as well as other notifications to determine your participation status in the study.

Volunteer Sign up

Volunteer Sign-up

Participate in medical studies to develop new diagnostic and clinical treatments and improve current standards of care.

Sign Up Now!

If you need assistance finding a non-cancer study or if you have any questions, please email