MRI and Biological Markers of Acute E-Cigarette Exposure in Smokers and Vapers

Brief description of study

This research study is being conducted to examine the effects of electronic cigarette aerosol, in the presence and absence of nicotine, on the endothelium, a layer of cells that act as a protective barrier and play an important part in controlling the flow of blood around the body.

Detailed description of study

Smokers and vapers: This group will complete three study visits. During each visit blood is drawn twice, an MRI is performed twice, and a smoking challenge is completed. No more than 30, and no fewer than 3 days can pass between each visit. A parking voucher and monetary compensation will be provided for each visit ($150 for every visit completed, $450 in total).

Nonsmokers: This group will complete one study visit during which blood is drawn once, one MRI is performed, and a hematocrit measurement is taken. A parking voucher and monetary compensation will be provided ($100 for one visit).

Eligibility of study

You may be eligible for this study if you meet the following criteria:

Conditions:
vapers,smokers,non-smokers,vape,cigarettes,smoking
Age: Between 18 Years - 45 Years
Gender: All

Smokers, vapers, and nonsmokers with no symptomatic cardiovascular or pulmonary disorders, and a body mass index between 18.5 and 30. Potential subjects will be asked to complete a brief eligibility screening. This consists of a phone call with a study coordinator.

Updated on 09 Mar 2024. Study ID: 850432

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