FDG/PET study: Relationship between brain and heart glucose metabolism in Alcohol Use Disorder

FDG/PET study: Relationship between brain and heart glucose metabolism in Alcohol Use Disorder

Brief description of study

The goal of this study is to learn more about how a nutritional supplement “ketone ester” (deltaG) has an effect on brain and heart function and on alcohol consumption in individuals with and without alcohol use disorder. The research team will study this using Fluorodeoxyglucose (FDG) Positron Emission Tomography/Computed Tomography (PET/CT) scans after a single dose of ketone ester and at baseline (no drink).

The duration of the study is up to 8 weeks. The study will take place on the Penn Medicine Center City/ University of Pennsylvania campus.
The research team is looking for 10 individuals with Alcohol Use Disorder, and 10 healthy control participants.
You may be compensated up to $685 for participation till completion of the study.

Detailed description of study

  • If you agree to join the study, you will be asked to complete the following research procedures.
  • Drinking a nutritional supplement ketone ester during one scanning visit.
  • Two FDG-PET/CT scans
  • Two echocardiograms before the FDG-PET/CT scans.
  • An MRI scan of the brain.
  • Blood draws for measurements of glucose or other testing
Contact the research team using the form below, if you are interested and would like to know more. 

Eligibility of study

You may be eligible for this study if you meet the following criteria:

  • Conditions:
    alcohol,alcohol use disorder
  • Age: Between 21 Years - 65 Years
  • Gender: All


Updated on 21 Jun 2023. Study ID: 848992

Interested in the study

Select a study center that’s convenient for you, and get in touch with the study team.

Contact a study center