HVTN 706 - A Multi-center, Randomized, Double-blind, Placebo-controlled Phase 3 Efficacy Study of a Heterologous Vaccine Regimen of Ad26.Mos4.HIV and Adjuvanted Clade C gp140 and Mosaic gp140 to Prevent HIV-1 Infection Among Cis-gender Men and Transgender Individuals who Have Sex with Cis-gender Men and/or Transgender Individuals

HVTN 706 - A Multi-center, Randomized, Double-blind, Placebo-controlled Phase 3 Efficacy Study of a Heterologous Vaccine Regimen of Ad26.Mos4.HIV and Adjuvanted Clade C gp140 and Mosaic gp140 to Prevent HIV-1 Infection Among Cis-gender Men and Transgender Individuals who Have Sex with Cis-gender Men and/or Transgender Individuals

Brief description of study

  1. Janssen Vaccines and Prevention B.V., the HIV Vaccine Trials Network (HVTN), and University of Pennsylvania, PENN Prevention Unit are doing a study to test a combination of HIV vaccines. HIV is the virus that causes AIDS. The researcher in charge of this study at this clinic is Dr. Ian Frank. Janssen Vaccines & Prevention, B.V., one of the companies of Johnson and Johnson and the U.S. National Institutes of Health (NIH) are paying for the study.

Detailed description of study

    This study is being done to answer several questions.
    • Are the study vaccines safe to give to people?
    • Are people able to take the study vaccines without becoming too uncomfortable?
    • How do people’s immune systems respond to the study vaccines? (Your immune systemprotects you from disease.)
    • Do the study vaccines prevent people from getting infected with HIV?

    Eligibility of study

    You may be eligible for this study if you meet the following criteria:

    • Conditions:
      Healthy,HIV
    • Age: Between 18 Years - 59 Years
    • Gender: All

    We are looking for:
    Cis-gender man having sex with cis-gender men and/or transgender individuals,
    OR 
    Transgender woman having sex with cis-gender men and/or transgender individuals,
    OR 
    Transgender man having sex with cis-gender men and/or transgender women (transgender man having sex exclusively with transgender men is excluded), 
    OR 
    Gender non-conforming individual having receptive or insertive anal and/or vaginal condomless intercourse

    Updated on 04 Jul 2023. Study ID: 834148

    Interested in the study

    Select a study center that’s convenient for you, and get in touch with the study team.

    Contact a study center