Integrating HIV Prevention Gender-Affirmative Medical Care and Peer Health Navigation for Transgender Women in the Americas: A Vanguard Study

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Study Overview

This study is being done to learn whether to provide HIV prevention services in conjunction with gender-affirming hormone therapy for transgender women and assess the safety of this intervention in the United States and Brazil.

All participants will be offered medications to prevent HIV, known as Pre-exposure prophylaxis (PrEP). These medications are called Descovy® and Truvada®. When used every day, it most likely will help you to avoid becoming infected with HIV.

Study Description

The HIV Prevention Trials Network (HPTN) and Penn HIV Prevention CRS are doing this study to learn how best to prevent transgender women from acquiring HIV in the United States and Brazil.

Participants will be given the opportunity to take medications to prevent HIV. The medication to prevent becoming infected with HIV is sometimes called pre-exposure prophylaxis or “PrEP.” PrEP is a way to prevent HIV infection for people who do not have HIV (the virus that causes AIDS) by taking a pill every day. HIV is the virus that causes Acquired Immunodeficiency Syndrome, or AIDS. The drugs being used for PrEP in this study are called Descovy® and Truvada®. Descovy® and Truvada® are pills that have two drugs in them called “emtricitabine” and one of two forms of “tenofovir”. These medicines are also used in combination with other medicines to treat HIV. You and your study clinician will make a choice of which PrEP medicine is best for you together.

  • Study Identifier: 844745

Recruitment Status


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