Lymph Node Fine Needle Aspiration to Study Immune Responses to Vaccinations
Brief description of study
The purpose of this study is to see how healthy adults
respond to COVID-19 vaccination. Part of the study also involves studying the
vaccine response among patients who are immunocompromised as a result the
medical treatments they receive. We are enrolling both healthy adults (>18
yrs) as well as adult patients who have undergone kidney transplant in this
study. The study will evaluate vaccine responses in the blood and in lymph
nodes (where early immune reactions begin after vaccination).
Detailed description of study
The study consists of a screening visit that could be done
in person, by phone, or by telemedicine. After enrollment, the study involves
up to 4 study visits as follows:
Visit 1, prior to
vaccination: blood draw (approx. 20 min).
Visit 2, approx.
14 days after 1st vaccination: blood draw and fine needle aspiration
(FNA) of lymph nodes under your armpit (approx. 1-2 hours).
Visit 3, 7-10
days after 2nd vaccination (if you have received a two-dose
vaccine): blood draw and fine needle aspiration (FNA) of lymph nodes under your
armpit (approx. 1-2 hours).
Visit 4, 3-6
months after last vaccine dose: blood draw and fine needle aspiration (FNA) of
lymph nodes under your armpit (approx. 1-2 hours).
The study team will not be able to provide the COVID-19
vaccine as part of the study. You would be eligible to participate in this
study if you have already made arrangements for vaccination or are planning to
soon.
The compensation for participation in this study is $100 for
each FNA visit for a total of $300.
Eligibility of study
You may be eligible for this study if you meet the following criteria:
-
Conditions:
covid-19,covid19,vaccine,immunocompromised,healthy volunteers,kidney transplant
-
Age: Between 18 Years - 99 Years
-
Gender: All
Updated on
08 Jul 2022.
Study ID: 844882
