Duration and Nature of Long-Term Immunosuppression After Neurosurgical Procedure

Duration and Nature of Long-Term Immunosuppression After Neurosurgical Procedure

Brief description of study

Patients greater than 18 years of age undergoing a neurosurgical procedure at Penn Medicine will be approached for enrollment. Currently, this study is open only at the HUP and Penn Presbyterian Medical Center locations.

Current research suggests that severe bodily stress caused by surgery may impair the immune system's ability to coordinate activation and suppression of the immune response. Neurological injury following neurotrauma, aneurysmal subarachnoid hemorrhage, and invasive neurosurgery have all been suggested as triggers of abnormal immune activation and loss of coordination. This research aims to investigate and characterize abberations in immune function after primary neurosurgical procedures. Study findings may increase general knowledge about the effects of neurosurgical procedures on the immune system, and therefore can potentially affect future medical education and clinical practice.

Eligibility of study

You may be eligible for this study if you meet the following criteria:

  • Conditions:
    neurosurgery,immune
  • Age: Between 18 Years - 99 Years
  • Gender: All


Updated on 15 Jan 2021. Study ID: 844325

Interested in the study

Select a study center that’s convenient for you, and get in touch with the study team.

Contact a study center