This research is being done to see if women who have sickle cell disease (SCD) experience any difference in their pain while using a hormonal implant as compared to when not using a hormonal implant (Nexplanon).
We are seeking women between the ages of 18 and 45 who have been diagnosed with SCD and have had at least 3 vaso-occlusive pain episodes in the previous 6 months.
If you agree to join the study, you will be asked to complete the following research procedures: you will complete a 3-month “baseline” with no use of hormonal contraception (such as the birth control pill, ring, or injection), and then will have a contraceptive implant (Nexplanon) placed for 6 months. Your participation will last for a total of 9 months, with 3 in-person visits with a urine pregnancy test, blood draw, and surveys, as well as the completion of a daily text message questionnaire.
Study Identifier: 844708
Contact the research team to learn more about this study.