Physiologic Response to Non-Invasive Respiratory Support in Obese Patients with Acute Hypoxemic Respiratory Failure from COVID-19

Physiologic Response to Non-Invasive Respiratory Support in Obese Patients with Acute Hypoxemic Respiratory Failure from COVID-19

Brief description of study

This research study only enrolls hospitalized patients at Penn Medicine.

The purpose of the study is to assess differences in respiratory and ventilation parameters between HFNC and helmet CPAP in obese patients with COVID-19 AHRF. We will enroll patients admitted to a HUP ICU with COVID-19 who have an obese BMI and are receiving HFNC. Patients will be monitored with electrical impedance tomography (EIT) in addition to standard ICU monitors. Patients will receive alternating treatment with HFNC and helmet CPAP over a 90 minute study period.

Eligibility of study

You may be eligible for this study if you meet the following criteria:

  • Conditions:
    COVID-19, ICU admitted, obese, low risk of intubation
  • Age: Between 18 Years - 99 Years
  • Gender: All


Updated on 19 Jul 2021. Study ID: 844516

Interested in the study

Select a study center that’s convenient for you, and get in touch with the study team.

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