The goal of this study is to learn more about how a nutritional supplement “ketone ester” (DeltaG) has an effect on brain function and on alcohol consumption in individuals with alcohol use disorder. We will study this using Magnetic Resonance Imaging (MRI) scans.
will be compensated/reimbursed for their time and effort. Participants may be
compensated up to $677 if they complete the main study and the sub-study.
The research team is currently seeking 2 groups of
participants: drinkers and non-drinkers (control group). Please review the
criteria for participation listed in the Additional Information section, before
contacting the research team.
Group 1: 20 participants with
alcohol use disorder
Group 2: 10 non-drinkers or healthy
that agree and qualify to join the study, will be asked to complete the
following research procedures:
a nutritional supplement ketone ester
scans of the brain
draws for measurements of glucose or other testing
consumption: we will give you a tray with alcoholic drinks (i.e., vodka mixed
with diet soda of your choice) Participants will be asked to come to Penn
Medicine 3 times over a period of approximately 4 weeks.
Please read the criteria below. If you think you qualify, are interested and wish to learn
more, contact the research team using the form below.
Some of the criteria for Group 2-healthy controls/ non-drinkers include, but not limited to:
1. Age 21 years to 65 years old.
2. Participants must agree to not
consume alcohol beverages for 24 hours prior to laboratory sessions, and
consume less than 15 drinks per month.
3. Must be able to comfortably lie
flat on back for up to 2 hours in the MRI scanner or PET scanner.
Study Identifier: 844235
Contact the research team to learn more about this study.