Phase 2 Inovio COVID-19 Vaccine

Phase 2 Inovio COVID-19 Vaccine

Brief description of study

Phase 2/3 study of INO-4800 DNA vaccine for SARS-CoV-2 to assess safety, efficacy & immunogenicity of vaccine in health volunteers at high risk for SARS-CoV-2 exposure. INO-4800 1.0mg or placebo given by intradermal injection followed by electroporation using CELLECTRA2000 investigational device at Day 0 and Day 28. Procedures include physicals, biospecimen collection and subject diaries over 8 outpatient visits plus phone calls.

Detailed description of study

If you agree to join the study, you will be asked to complete the following research procedures: 

Screening, vaccination visits (2 of them) and collection of medical information as well as blood to evaluate the safety and the ability of the vaccine to make an immune response against the coronavirus.
Follow-up visits via phone and in-person
Your participation will last for about 13 months. 

Eligibility of study

You may be eligible for this study if you meet the following criteria:

  • Conditions:
    COVID-19,COVID19,vaccine,healthy volunteers
  • Age: Between 18 Years - 50 Years
  • Gender: All

INCLUSION CRITERIA:
Men and non-pregnant women 18 years of age or older;
Assessed by the Investigator to be healthy based on medical history, vital signs and physical examination performed at Screening;
Working or residing in an environment with high risk of exposure to SARS-CoV-2 for whom exposure may be relatively prolonged or for whom personal protective equipment (PPE) may be inconsistently used, especially in confined settings:
Retail/service workers/educators (restaurant waitresses/waiters and bar workers, store cashiers, hairdressers and barbers, veterinary staff, daycare workers, Transportation Security Administration screening staff, school teachers and
college professors teaching in-person classes), factory workers (when working in confined settings with large numbers of
employees), Drivers providing bus, taxi or shared ride services (e.g., Uber, Lyft) nursing home staff or correctional facility staff
Retirement community residents or adult day program attendees who are regularly eating, socializing and/or exercising in common areas First responders (emergency medical technicians, police who are regularly assigned on patrol. 

Updated on 26 Jul 2021. Study ID: 843500

Interested in the study

Select a study center that’s convenient for you, and get in touch with the study team.

Contact a study center