Characterizing SARS-CoV-2-specific Immunity in Individuals Who Have Recovered From COVID-19

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Study Overview

HVTN 405/HPTN 1901 will describe immune responses in study participants with a history of recovering from SARS- CoV-2 infection. A main aim of HVTN 405/HPTN 1901 is to develop antibody assays that can be reliably used to detect SARS-CoV-2 infection in vaccine and monoclonal antibody studies to prevent COVID-19. This information will be critical in illuminating the path to the development and testing of safe and effective vaccine and antibody interventions to prevent COVID-19.

Study Description

How will study participants contribute to HVTN 405/HPTN 1901? 
  • Participants will attend one required clinic visit and will have the option to attend additional clinic visits two, four and twelve months after the initial visit. 
  • Each visit includes a questionnaire, blood draw and optional nasal sampling. 
  • Individuals who have not fully recovered from their infection (i.e., still have symptoms or had a positive test within the preceding two weeks) will not be enrolled. 

  • Study Identifier: 843127

Recruitment Status

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