Evaluation of in vivo Neuroinflammation Using 18F-NOS (PET/CT) in HIV Positive and Negative Subjects with Opioid Use Disorder and Healthy Controls
Brief description of study
Study Purpose: The goal of this study is to learn more about how opiate use and HIV affects inflammation in the brain. We will study this using a type of Positron Emission Tomography (PET/CT) scan using a radioactive imaging drug called 18F-NOS that can be used to measure inflammation in the brain.
Procedures: If you agree to join the study, you will be asked to complete the following research procedures:
- 18F-NOS PET/CT of the brain
- Placement of an arterial catheter to perform blood draws during the scan
- Blood draw for measurement of research inflammatory markers or other testing
- Brain MRI scan if you have not had one within 1 year that is up to study standards
Eligibility of study
You may be eligible for this study if you meet the following criteria:
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Conditions:
HIV,opioid use,healthy volunteers
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Age: Between 18 Years - 60 Years
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Gender: All
Updated on
19 Mar 2024.
Study ID: 842717
