Efficacy, Safety, and Tolerability Topical Nasal Spray in the Prevention of SARS-CoV-2 Infection in Healthcare Personnel

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Study Overview

The purpose of this study is to assess the effectiveness, safety, and tolerability of GLS-1200 to prevent SARS-CoV-2 infection in healthcare personnel. GLS-1200 contains quinine diluted in saline (salt water). Pre-clinical studies have shown that quinine stimulates nasal cells to secrete compounds that may prevent growth of bacteria and reduce viruses from reproducing. 

Study Description

Treatment: Participants will be randomized to either quinine or placebo group (saline or salt water) at a 2:1 ratio. 
 Duration of the Study: Participants will self-administer study drug three times daily (TID) for 4 weeks. A follow-up visit will be made at 6 weeks to assess participant health since some cases of SARS-CoV-2 infection may not be apparent until after the treatment period has ended.

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  • Study Identifier: 843133

Recruitment Status

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