Assessment of Chronic Lung Allograft Dysfunction Using Single-Breath & Multi-Breath Hyperpolarized Xenon 129 MRI

Brief description of study

The research study is being conducted to determine the effectiveness of using hyperpolarized xenon-129 (HP 129-Xe) magnetic resonance imaging (MRI) in diagnosing and predicting the clinical course of patients who received lung transplantation.

Detailed description of study

If you agree to join the study, you will be asked to complete the following research procedures: • Complete a brief MRI safety questionnaire • Practice the breathing procedure that will be performed during the study • MRI scanning using the inhaled MRI contrast agent Hyperpolarized Xenon129 (HP 129Xe) Your participation will last for up to two years. Over the course of your participation, you will be contacted to attend up to five follow up visits after your initial baseline visit.

Eligibility of study

You may be eligible for this study if you meet the following criteria:

Conditions:
pulmonary,lung transplant
Age: Between 18 Years - 90 Years
Gender: All

Patients who have received lung transplantation.

*Healthy males or females age 18+ are also eligible for this study.

Updated on 09 Mar 2024. Study ID: 834759

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