Randomized Study of Cranial Blocks for Postoperative Anesthesia to Reduce Pain and Postoperative Opioid Usage

Randomized Study of Cranial Blocks for Postoperative Anesthesia to Reduce Pain and Postoperative Opioid Usage

Brief description of study

The research study is being conducted to look at the effectiveness of analgesia (pain medication) by scalp nerve block with various medications that will help doctors to more effectively control pain after surgery and for a longer period of time. 


Detailed description of study

If you agree to join the study, on the morning of your procedure, you will be randomized into one of the 3 study groups by the research team. 

After your procedure, you will have your blood taken for 3 days to monitor for a potential drug interaction. You will then be asked to complete pain surveys while in the hospital. Participation in this clinical trial will not impact your clinical care and if you need standard of care pain medication, oral or intravenous, to control your pain after surgery, the clinical team will give it to you.

Your participation will last for the duration of your time in the hospital (until discharge). You will have an end-of-study visit at your follow-up appointment 4-6 weeks after your surgery.

Eligibility of study

You may be eligible for this study if you meet the following criteria:

  • Conditions:
    craniotomy
  • Age: Between 18 Years - 99 Years
  • Gender: All


Updated on 10 Jul 2023. Study ID: 834603

Interested in the study

Select a study center that’s convenient for you, and get in touch with the study team.

Contact a study center