INvestigation of the Gut microbiomE on STatin response (INGEST Study)
Brief description of study
We are looking for healthy volunteers to
participate in a study to see if a particular type of medication (statin) has
an impact on the kind of bacteria that are found in the gut, and if the gut
bacteria affects how the body responds to the medication. If you participate in
the study, you will be asked to take the medication or a placebo for 8 weeks. If you qualify, your participation would last
about 4 months, during which time there are 4 brief visits to the Hospital of the
University of Pennsylvania. Compensation is offered to eligible participants for completed study visits.
Detailed description of study
The study involves taking rosuvastatin 20 mg daily or
placebo pill (sugar pill) for 8 weeks. Samples collected at visits will include blood, urine, and stool along with vital signs and other measurements.
Eligibility of study
You may be eligible for this study if you meet the following criteria:
-
Conditions:
Healthy,Healthy Volunteer,statin,microbiome
-
Age: Between 18 Years - 65 Years
-
Gender: All
Participants must be non-smoking, non-vegan/vegetarian, healthy individuals who have not been diagnosed with chronic GI illnesses and do not take certain prescription or over-the counter medications/supplements/vitamins.
Criteria
Updated on
13 Dec 2023.
Study ID: 832874
