We are looking for healthy volunteers to
participate in a study to see if a particular type of medication (statin) has
an impact on the kind of bacteria that are found in the gut, and if the gut
bacteria affects how the body responds to the medication. If you participate in
the study, you will be asked to take the medication or a placebo for 8 weeks. If you qualify, your participation would last
about 4 months during which time there are 4 brief visits to the Hospital of the
University of Pennsylvania.
The study involves taking rosuvastatin 20 mg daily or
placebo pill (sugar pill) for 8 weeks. Samples collected at visits will include blood, urine, and stool along with vital signs and other measurements.